1-Indanamine

1-Indanamine Structure
1-Indanamine structure
Common Name 1-Indanamine
CAS Number 34698-41-4 Molecular Weight 133.190
Density 1.1±0.1 g/cm3 Boiling Point 225.0±19.0 °C at 760 mmHg
Molecular Formula C9H11N Melting Point 15 °C(lit.)
MSDS Chinese USA Flash Point 94.4±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines.

Chirality 23(4) , 349-53, (2011)

A new colorimetric chiral sensor material consisting of three different functional sites such as chromophore (2,4-dinitrophenylazophenol dye), binding site (crown ether), and chiral barrier (3,3'-diphenyl-1,1'-binaphthyl group) was prepared and applied to the...

Laser-induced fluorescence and single vibronic level emission spectroscopy of chiral (R)-1-aminoindan and some of its clusters in a supersonic jet.

Phys. Chem. Chem. Phys. 8(8) , 1001-6, (2006)

Two low energy conformers of the chiral (R)-1-aminoindan molecule are identified in supersonic jet and their ground and excited states vibrational spectroscopy has been investigated by laser-induced fluorescence (LIF) excitation and single vibronic level (SVL...

Oxygen-18 studies on the oxidative deamination mechanism of alicyclic primary amines in rabbit liver microsomes.

Arch. Biochem. Biophys. 215(2) , 433-43, (1982)

Low-frequency vibrations specific for conformers of 1-aminoindan studied by UV-UV hole-burning spectroscopy.

J. Chem. Phys. 126(21) , 214304, (2007)

The UV-UV hole-burning spectra of the jet-cooled 1-aminoindan were measured for the first time. Complicated spectral features observed in the laser-induced fluorescence excitation spectrum due to two conformers, R and B, were firmly separated. On the basis of...

Rapid enantioseparation of 1-aminoindan by microchip electrophoresis with linear-imaging UV detection.

Anal. Sci. 21(1) , 61-5, (2005)

Chiral separations of 1-aminoindan (AI) by cyclodextrin electrokinetic chromatography (CDEKC) were investigated on microfluidic quartz chips. By using a microchip electrophoresis (MCE) instrument equipped with a linear-imaging UV detector, the separation proc...

Pharmacological comparison between the actions of methamphetamine and 1-aminoindan stereoisomers on sympathetic nervous function in rat vas deferens.

Eur. J. Pharmacol. 472(3) , 173-7, (2003)

The selective monoamine oxidase-B inhibitor selegiline (deprenyl) causes sympathomimetic effects and is metabolised to R(-)-methamphetamine and R(-)-amphetamine. The new monoamine oxidase-B inhibitor rasagiline is devoid of sympathomimetic effects and is meta...

Separation of chiral primary amino compounds by forming a sandwiched complex in reversed-phase high performance liquid chromatography.

J. Chromatogr. A. 1217(30) , 4965-70, (2010)

Separation of chiral primary amino compounds was efficiently achieved under reversed-phase high performance liquid chromatography (RP-HPLC) conditions using a mixture of non-chiral crown ether (18-crown-6) and dimethyl-beta-cyclodextrin (DM-beta-CD) in the mo...

1-Aminoindanes as novel motif with potential atypical antipsychotic properties.

Bioorg. Med. Chem. Lett. 18(2) , 489-93, (2008)

As part of an on-going effort to investigate the chemical space requirements for D(2)/5-HT(2A) receptor antagonists as atypical antipsychotics, new 1-aminoindanes were synthesized. The replacement of the heterocycle (oxindole) in ziprasidone with a carbocycle...

Separation of cis-/trans-diastereomers and enantiomers of aminoindanol and aminoindan using capillary electrophoresis.

J. Capillary Electrophor. 4(6) , 279-85, (1997)

Aminoindanol poses an interesting separation problem because it contains two chiral centers and exists as four stereoisomers. The capillary electrophoretic separation of the cis- and the larger trans-diastereomers of aminoindanol is simply achieved by pH cont...

Electropharmacograms of rasagiline, its metabolite aminoindan and selegiline in the freely moving rat.

Neuropsychobiology 62(4) , 213-20, (2010)

Rasagiline and selegiline are classified as monoamine oxidase B (MAO-B) inhibitors. The present investigation deals with time-dependent electrical frequency changes (electropharmacograms) induced by these, as well as by aminoindan, the major metabolite of ras...