N-Me-DL-Ala-OH.HCl
N-Me-DL-Ala-OH.HCl structure
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Common Name | N-Me-DL-Ala-OH.HCl | ||
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| CAS Number | 600-21-5 | Molecular Weight | 103.120 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 190.1±23.0 °C at 760 mmHg | |
| Molecular Formula | C4H9NO2 | Melting Point | 317CºC | |
| MSDS | Chinese USA | Flash Point | 68.8±22.6 °C | |
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1H-NMR and 13C-NMR investigation of complexes of Mn2+ with ocytocin analogues in (2H6)dimethylsulfoxide.
Eur. J. Biochem. 240(1) , 118-24, (1996) Several ocytocin analogues were synthesised by substitution of the Pro residue with sarcosine or N-methylalanine, the glutamine residue with threonine and one of the cysteines with 2-mercaptopropionic acid. All the derivatives were investigated by NMR in dime... |
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Transport of L-alanine in cultured human fibroblasts: evidence for two kinetically distinguishable systems.
J. Cell Physiol. 109(1) , 37-43, (1981) The transport of L-alanine in human diploid fibroblasts was investigated. Transport measurements were performed on subcultures between the third and eighth passages with subconfluent cells growing on glass coverslips. Kinetic analysis of approximate initial r... |
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Monomeric sarcosine oxidase: 2. Kinetic studies with sarcosine, alternate substrates, and a substrate analogue.
Biochemistry 39 , 8825-9, (2000) Monomeric sarcosine oxidase (MSOX) is a flavoenzyme that catalyzes the oxidative demethylation of sarcosine (N-methylglycine) to yield glycine, formaldehyde, and hydrogen peroxide. MSOX can oxidize other secondary amino acids (N-methyl-L-alanine, N-ethylglyci... |
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Design, synthesis and pharmacological characterization of endomorphin analogues with non-cyclic amino acid residues in position 2.
Basic Clin Pharmacol Toxicol. 106 , 106-113, (2010) A series of endomorphin-1 (EM-1) and endomorphin-2 (EM-2) analogues, containing non-cyclic amino acids (Ala, D-Ala, beta-Ala, NMeAla, D-NMeAla or Sar) instead of Pro in position 2 was synthesized, where NMeAla = N-methylalanine and Sar = N-methylglycine, sarc... |
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Amino acid efflux in the isolated perfused rat pancreas: trans-stimulation by extracellular amino acids.
J. Physiol. 416 , 485-502, (1989) 1. Epithelial uptake and efflux of the non-metabolized system A analogue 2-methylaminoisobutyric acid (MeAIB) and L-serine were studied in the isolated perfused rat pancreas using a dual tracer loading and wash-out technique. Uptakes of 2-[14C]MeAIB and L-[3H... |
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In vitro and in vivo antitumor effects of novel actinomycin D analogs with amino acid substituted in the cyclic depsipeptides.
Peptides 31 , 568-573, (2010) The actinomycin D (AMD) analogs in which the D-valine residues (the second amino acid residue in the cyclic depsipeptide of AMD) and the N-methyl-L-valine residues (the fifth amino acid residue in the cyclic depsipeptide of AMD) were replaced with D-Phe or l-... |
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Detection of BMAA in the human central nervous system.
Neuroscience 292 , 137-47, (2015) Amyotrophic lateral sclerosis (ALS) is an extremely devastating neurodegenerative disease with an obscure etiology. The amino acid β-N-methylamino-l-alanine (BMAA) produced by globally widespread phytoplankton has been implicated in the etiology of human moto... |
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Analogue-resistant mutants of Azotobacter chroococcum derepressed for nitrogenase activity and early ammonia excretion having potential as inoculants for cereal crops.
Indian J. Exp. Biol. 38(4) , 373-8, (2000) Spontaneous mutants resistant to methionine sulfoximine (Msx), methyl alanine (Mal) and methyl ammonium chloride (Mac) were derived from A. chroococcum strain A103. Msx and Mal-resistant mutants expressed 1.73 to 10.98% of the fully derepressed nitrogenase ac... |
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Inhibition of sodium-dependent L-leucine uptake in rat brain synaptosomes.
Biochem. Pharmacol. 39(5) , 955-8, (1990) Synaptosomes isolated from adult rat cerebral cortices were used for studying the uptake of L-leucine by the Na(+)-dependent route. Three non-metabolizable amino acid analogues, which had been used previously to discriminate the Na(+)-dependent A-type uptake ... |
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Synthesis and some pharmacological properties of oxytocin and vasopressin analogues with sarcosine or N-methyl-L-alanine in position 7.
J. Med. Chem. 26(4) , 555-9, (1983) Eight analogues of oxytocin and arginine-vasopressin were synthesized, in which the proline residue in position 7 was replaced by either sarcosine or N-methylalanine; some of the pharmacological properties of these analogues were evaluated. In peptides contai... |