Cytosporone B

Cytosporone B Structure
Cytosporone B structure
Common Name Cytosporone B
CAS Number 321661-62-5 Molecular Weight 322.39600
Density N/A Boiling Point N/A
Molecular Formula C18H26O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

NUR77 exerts a protective effect against inflammatory bowel disease by negatively regulating the TRAF6/TLR-IL-1R signalling axis.

J. Pathol. 238 , 457-69, (2016)

Nur77, an immediate-early response gene, participates in a wide range of biological functions. Its human homologue, NUR77, is known by several names and has the HGNC-approved gene symbol NR4A1. However, the role of Nur77 in inflammatory bowel disease (IBD) an...

Histone acetylation regulates orphan nuclear receptor NR4A1 expression in hypercholesterolaemia.

Clin. Sci. (Lond.) 129 , 1151-61, (2015)

Hypercholesterolaemia and inflammation are correlated with atherogenesis. Orphan nuclear receptor NR4A1, as a key regulator of inflammation, is closely associated with lipid levels in vivo. However, the mechanism by which lipids regulate NR4A1 expression rema...