PFK-015

PFK-015 Structure
PFK-015 structure
Common Name PFK-015
CAS Number 4382-63-2 Molecular Weight 260.290
Density 1.2±0.1 g/cm3 Boiling Point 464.4±45.0 °C at 760 mmHg
Molecular Formula C17H12N2O Melting Point N/A
MSDS USA Flash Point 233.5±35.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells.

Cell Death Dis. 6 , e2005, (2015)

Rasfonin is a fungal secondary metabolite with demonstrated antitumor effects. However, the underlying mechanism of the regulatory role in autophagy initiated by rasfonin is largely unknown. Moreover, the function of Akt to positively mediate the induced auto...