Docusate sodium
Docusate sodium structure
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Common Name | Docusate sodium | ||
|---|---|---|---|---|
| CAS Number | 577-11-7 | Molecular Weight | 444.558 | |
| Density | 1.1 | Boiling Point | N/A | |
| Molecular Formula | C20H37NaO7S | Melting Point | 173-179 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 199ºC | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Preparation of gentamicin dioctyl sulfosuccinate loaded poly(trimethylene carbonate) matrices intended for the treatment of orthopaedic infections.
Clin. Hemorheol. Microcirc. 60 , 89-98, (2015) Infection is a common problem in trauma and orthopaedic surgery. Antibiotic-loaded biomaterials are used locally to clear infections as an adjunct to systemic antibiotics. Gentamicin-sulphate (GEN-SULPH) is commonly used in antibiotic-loaded biomaterials, alt... |
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Multivalent linkers for improved covalent binding of oligonucleotides to dye-doped silica nanoparticles.
Nanotechnology 26 , 365703, (2015) This paper describes the fabrication of oligonucleotide-coated Cy5-doped silica nanoparticles using a combination of multivalent linkers and their use in surface-based DNA sandwich hybridization assays. Dipodal silane is introduced as a means to fabricate ami... |
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Nanosized silver (II) pyridoxine complex to cause greater inflammatory response and less cytotoxicity to RAW264.7 macrophage cells.
Nanoscale Res. Lett. 10 , 140, (2015) With advancements in nanotechnology, silver has been engineered into a nanometre size and has attracted great research interest for use in the treatment of wounds. Silver nanoparticles (AgNPs) have emerged as a potential alternative to conventional antibiotic... |
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Preparation of concentrated stable fenofibrate suspensions via liquid antisolvent precipitation.
Drug Dev. Ind. Pharm. 40(12) , 1693-703, (2014) A major challenge in achieving size stability for relatively high concentration of fine particles from poorly water-soluble drug fenofibrate (FNB) is addressed through T-mixing based liquid antisolvent precipitation in the presence of ultrasonication and judi... |
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Organically modified titania nanoparticles for sustained drug release applications.
J. Colloid. Interface Sci. 456 , 59-65, (2015) In this paper, we report the synthesis, characterization of drug-doped organically modified titania nanoparticles, and their applications in sustained drug release. The drug-doped nanoparticles were synthesized in the hydrophobic core of oil-in-water microemu... |
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Surfactant choice and the physical stability of nanosuspensions as a function of pH
Int. J. Pharm. 439(1-2) , 1-7, (2012) Nanosuspensions of the example compounds ketoconazole and itraconazole were shown to aggregate upon reducing the pH to levels comparable to that known to exist in the stomach. Manipulation of the surfactant/polymer ratio in the suspension vehicle did not eluc... |
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Laser-induced fluorescence reader with a turbidimetric system for sandwich-type immunoassay using nanoparticles.
Anal. Chim. Acta 883 , 32-6, (2015) A unique laser-induced fluorescence (LIF) reader equipped with a turbidimetric system was developed for a sandwich-type immunoassay using nanoparticles. The system was specifically designed to reduce experimental error caused by particle loss, aggregation and... |
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Ototoxicity of intratympanic docusate sodium and mineral oil in the guinea pig.
Otolaryngol. Head Neck Surg. 146(3) , 455-60, (2012) (1) To evaluate the ototoxic potential of docusate sodium and mineral oil and (2) to compare the cerumenolytic properties of these agents to water and a commercially available product.Prospective animal study.Docusate sodium and mineral oil are being used to ... |
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Correlating proton transfer dynamics to probe location in confined environments.
J. Am. Chem. Soc. 134(29) , 11904-7, (2012) The dramatic impact of differing environments on proton transfer dynamics of the photoacid HPTS prompted us to investigate these systems with two highly complementary methods: ultrafast time-resolved transient absorption and two-dimensional NMR spectroscopies... |
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Irradiation induced fluorescence enhancement in PEGylated cyanine-based NIR nano- and mesoscale GUMBOS.
Langmuir 28(40) , 14415-23, (2012) We report on the synthesis and characterization of a PEGylated IR786 GUMBOS (Group of Uniform Materials Based on Organic Salts). The synthesis of this material was accomplished using a three step protocol: (1) substitution of chloride on the cyclohexenyl ring... |