2,2',4'-Trichloroacetophenone

2,2',4'-Trichloroacetophenone Structure
2,2',4'-Trichloroacetophenone structure
Common Name 2,2',4'-Trichloroacetophenone
CAS Number 4252-78-2 Molecular Weight 223.484
Density 1.4±0.1 g/cm3 Boiling Point 292.2±25.0 °C at 760 mmHg
Molecular Formula C8H5Cl3O Melting Point 47-54 °C(lit.)
MSDS Chinese USA Flash Point 122.1±23.7 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Glutathione-dependent reductive dehalogenation of 2,2',4'-trichloroacetophenone to 2',4'-dichloroacetophenone.

Biochem. Pharmacol. 31(23) , 3885-90, (1982)

alpha-Haloketones are highly reactive compounds, which are known to undergo enzymatic reduction to methyl ketones. The objective of this research was to characterize the enzymes involved in this reaction and to investigate the mechanism of the reaction. 2,2',...

Clean and efficient microwave-solvent-free synthesis of 1-(2', 4'-dichlorophenacyl) azoles. Pérez ER, et al.

Tetrahedron 59(6) , 865-70, (2003)