3-Aminopyridine

3-Aminopyridine Structure
3-Aminopyridine structure
Common Name 3-Aminopyridine
CAS Number 462-08-8 Molecular Weight 94.115
Density 1.1±0.1 g/cm3 Boiling Point 251.0±0.0 °C at 760 mmHg
Molecular Formula C5H6N2 Melting Point 60-63 °C(lit.)
MSDS Chinese USA Flash Point 126.0±7.0 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Anharmonic vibrational analysis of 3,4-diaminopyridine and 3-aminopyridine by density functional theory calculations.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 76(5) , 502-12, (2010)

In this work, we will report a combined experimental and theoretical study on molecular structure and vibrational analysis of 3,4-diaminopyridine (3,4-DAP) and 3-aminopyridine (3-AP). The Fourier transform infrared and Fourier transform Raman spectra of 3,4-D...

Evaluation of electrophilic heteroaromatic substitution: synthesis of heteroaromatic-fused pyrimidine derivatives via sequential three-component heterocyclization.

J. Org. Chem. 77(19) , 8492-500, (2012)

A new sequential three-component heterocyclization was developed by reacting aromatic and heterocyclic substrates, including aminobenzenes, 1-aminonaphthalene, 2-aminopyrazines, 5-aminopyrazoles, 3-aminopyridine, 5-aminopyrimidine, 5-aminoquinoline, and 8-ami...

The significance of the temporal bond polarizabilty relaxation of 2- and 3-aminopyridine by 514.5 nm excitation for the nonresonant Raman virtual states.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 71(4) , 1588-93, (2008)

Our algorithm [B. Tian, G. Wu, G. Liu, J. Chem. Phys. 87 (1987) 7300] is introduced to obtain the temporal bond polarizabilities of 2- and 3-aminopyridine from their Raman intensities, which supply fruitful electronic information of the nonresonant Raman exci...

Surface complexation modeling of the sorption of 2-, 3-, and 4-aminopyridine by montmorillonite.

J. Colloid. Interface Sci. 284(2) , 383-92, (2005)

The sorption of 2-, 3-, and 4-aminopyridine on K-saturated Wyoming (SWy-K) and Texas (STx-K) and Ca-enriched Texas (STx-Ca) montmorillonite was measured at 25 degrees C with 10 mM KNO(3) or 3.3 mM Ca(NO(3))(2) as the background electrolyte. The aminopyridines...

Two salts of 5-sulfosalicylic acid and 3-aminopyridine.

Acta Crystallogr. C 63(Pt 11) , o667-70, (2007)

5-Sulfosalicylic acid (5-SSA) and 3-aminopyridine (3-APy) crystallize in the same solvent system, resulting in two kinds of 1:1 proton-transfer organic adduct, namely 3-aminopyridinium 3-carboxy-4-hydroxybenzenesulfonate monohydrate, C(5)H(7)N(2)(+).C(7)H(5)O...

Stimulation of substantia nigra pars reticulata suppresses neocortical seizures.

Brain Res. 574(1-2) , 237-43, (1992)

The effects of unilateral electrical stimulation of the substantia nigra pars reticulata (SNpr) on the electrocorticographic (ECoG) manifestations of seizures were studied in anesthetized rats. Epileptiform activity was provoked in the primary focus (Pf) by u...

An aminopyridine-sensitive, early outward current recorded in vivo in neurons of the precruciate cortex of cats using single-electrode voltage-clamp techniques.

Brain Res. 480(1-2) , 72-81, (1989)

Studies were performed in cortical neurons to determine if voltage- and time-dependent membrane currents could be recognized and characterized in the dynamic, in vivo state. Intracellular measurements made in neurons of the precruciate cortex of awake cats wi...

Properties of depolarizing plateau potentials in aminopyridine-induced ictal seizure foci of cat motor cortex.

Brain Res. 495(2) , 261-70, (1989)

The mechanisms of generation of self-sustained depolarizing plateau potentials (DPs) were studied in intracellular recordings in aminopyridine-induced ictal seizure foci in the motor cortex of the cat. In some experiments single-electrode voltage clamp techni...

Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis.

Pharmacol. Rep. 60(3) , 345-52, (2008)

We investigated the influence of recurrent epileptic seizures on the arachidonic acid (AA) cascade in platelets and brain microvessels, using [(14)C]AA as a tracer substrate and chromatographic determination. The recurrent epileptic seizures of male Wistar ra...

Interaction of 4-aminopyridine with [3H]phencyclidine receptors in rat brain homogenates.

Neurosci. Lett. 67(1) , 87-91, (1986)

The effect of 4-aminopyridine and its analogs on the specific binding of [3H]phencyclidine was investigated in rat brain homogenates. 4-Aminopyridine (4-AP) and 3,4-diaminopyridine displaced [3H]phencyclidine binding, while 3-aminopyridine was without effect....