methanesulfonyl fluoride

methanesulfonyl fluoride Structure
methanesulfonyl fluoride structure
Common Name methanesulfonyl fluoride
CAS Number 558-25-8 Molecular Weight 98.09670
Density 1.427 g/mL at 25 °C(lit.) Boiling Point 123-124 °C(lit.)
Molecular Formula CH3FO2S Melting Point N/A
MSDS Chinese USA Flash Point 28.5ºC
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Cloning and Expression of TNF Related Apoptosis Inducing Ligand in Nicotiana tabacum.

Iran. J. Pharm. Res. 14(1) , 189-201, (2015)

Molecular farming has been considered as a secure and economical approach for production of biopharmaceuticals. Human TNF Related Apoptosis Inducing Ligand (TRAIL) as a promising biopharmaceutical candidate has been produced in different expression hosts. How...

Characterisation of osteoprotegerin autoantibodies in coeliac disease.

Calcif. Tissue Int. 97 , 125-33, (2015)

Autoantibodies neutralising the effect of the bone regulatory cytokine osteoprotegerin (OPG) have been described in a patient with severe osteoporosis and coeliac disease. This study aimed to determine the prevalence and epitope specificity of autoantibodies ...

Purification and characterization of a fibrinolytic enzyme from Petasites japonicus.

Int. J. Biol. Macromol. 72 , 1159-67, (2015)

A new, direct-acting chymotrypsin-like fibrinolytic serine protease was purified from Petasites japonicus, a medicinal herb. The molecular mass of the discovered enzyme was estimated to be 40.0 kDa as determined using sodium dodecyl sulfate polyacrylamide gel...

Multiple binding of D-tubocurarine to acetylcholinesterase.

Biochem. Pharmacol. 35(14) , 2287-96, (1986)

The binding of D-tubocurarine (TC) to acetylcholinesterase (AChE) was studied using different methods of enzyme kinetics. The main results are as follows. TC reversibly inhibits the hydrolysis of different substrates of AChE with three different inhibition co...

Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected].

Br. J. Pharmacol. 103(1) , 1191-5, (1991)

1. Contractile responses and acetylcholine release evoked by nicotine in guinea-pig detrusor strips were determined by isotonic transducer and radioimmunoassay, respectively. Nicotine stimulated acetylcholine release and a contractile response in guinea-pig d...

Perioral behaviors induced by cholinesterase inhibitors: a controversial animal model.

Pharmacol. Biochem. Behav. 25(6) , 1217-21, (1986)

Perioral behaviors induced by neuroleptic drugs have been interpreted as an animal model of tardive dyskinesia. However, these behaviors have also been induced or enhanced by physostigmine, a cholinesterase inhibitor. The latter result is contradictory to the...

Methanesulfonyl fluoride (MSF): a double-blind, placebo-controlled study of safety and efficacy in the treatment of senile dementia of the Alzheimer type.

Alzheimer Dis. Assoc. Disord. 13(1) , 20-5, (1999)

The purpose of the present study was to evaluate methanesulfonyl fluoride (MSF), a very long-acting CNS-selective acetylcholinesterase (AChE) inhibitor, as a palliative treatment for senile dementia of the Alzheimer type (SDAT). In experiment I, MSF (0.03-0.1...

Chronic methanesulfonyl fluoride enhances one-trial per day reward learning in aged rats.

Neurobiol. Aging 14(4) , 393-5, (1993)

Aged (24-month-old) rats were treated chronically with methanesulfonyl fluoride (MSF), an acetylcholinesterase (AChE) inhibitor with selectivity for central nervous system AChE, or with injection vehicle alone. Twelve 0.22 mg/kg IP injections were given over ...

The effect of anticholinesterase drugs on the ionophoretically-evoked end-plate currents.

Pflugers Arch. 410(4-5) , 428-32, (1987)

In order to study the sensitivity of acetylcholine (ACh) receptors exposed to anticholinesterase drugs, the ionophoretically evoked end-plate currents (e.p.c.i) in frog sartorius muscle were studied. During treatment with prostigmine (PST, 3 microM) or methan...

Methanesulfonyl fluoride enhances one-trial reward learning in mid-aged rats.

Neurobiol. Aging 12(2) , 181-3, (1991)

In previous studies, 18-month-old rats have shown no significant retention 24 hours after the single acquisition trial in a one-trial discriminative reward learning task. In the present study, ten 18-month-old rats pretreated with 0.5 mg/kg MSF IP showed sign...