Oxothiazolidinecarboxylic acid
Oxothiazolidinecarboxylic acid structure
|
Common Name | Oxothiazolidinecarboxylic acid | ||
|---|---|---|---|---|
| CAS Number | 19771-63-2 | Molecular Weight | 147.152 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C4H5NO3S | Melting Point | 174 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Activation of the Nrf2-regulated antioxidant cell response inhibits HEMA-induced oxidative stress and supports cell viability.
Biomaterials 56 , 114-28, (2015) Oxidative stress due to increased formation of reactive oxygen species (ROS) in target cells of dental resin monomers like 2-hydroxyethyl methacrylate (HEMA) is a major mechanism underlying the disturbance of vital cell functions including mineralization and ... |
|
|
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Bioorg. Med. Chem. 19 , 6409-18, (2011) The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitative structure-activity relationship (3D QSAR) study has been... |
|
|
Protective effect of procysteine on Acinetobacter pneumonia in hyperoxic conditions.
J. Antimicrob. Chemother. 68(10) , 2305-10, (2013) Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality in critical care settings. Acinetobacter has become a leading cause of VAP. In particular, the appearance and spread of multidrug-resistant Acinetobacter is of great concer... |
|
|
The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
Molecules 18(3) , 3467-78, (2013) The aim of the study was to investigate the ameliorative effects and the mechanism of action of L-2-oxothiazolidine-4-carboxylate (OTC) on acetaminophen (APAP)-induced hepatotoxicity in mice. Mice were randomly divided into six groups: normal control group, A... |
|
|
Procysteine increases alcohol-depleted glutathione stores in rat plantaris following a period of abstinence.
Alcohol Alcohol. 45(6) , 495-500, (2010) To assess the effectiveness of procysteine (PRO) supplementation provided during a period of abstinence (ABS) on alcohol-induced skeletal muscle atrophy and oxidant stress.Age- and gender-matched Sprague-Dawley rats were fed the Lieber-DeCarli liquid diet con... |
|
|
Cytotoxicity of dentine bonding agents on human pulp cells is related to intracellular glutathione levels.
Int. Endod. J. 43(12) , 1091-7, (2010) To evaluate ex vivo the mechanisms of cytotoxicity of dentine bonding agents in human pulp cells in vitro.Human pulp cells were obtained from impacted third molars with informed consent and then cultured using an explant technique. Set specimens from Clearfil... |
|
|
Plant growth stimulation in Prunus species plantlets by BTH or OTC treatments under in vitro conditions.
J. Plant Physiol. 169(11) , 1074-83, (2012) The effects of benzothiadiazole (BTH) and L-2-oxothiazolidine-4-carboxylic acid (OTC) on the growth and viral content of micropropagated, Plum pox virus (PPV)-infected peach [(Prunus persica (L.) Batsch] 'GF305' plantlets were analyzed. Low BTH and OTC concen... |
|
|
Benzothiadiazole and l-2-oxothiazolidine-4-carboxylic acid reduce the severity of Sharka symptoms in pea leaves: effect on antioxidative metabolism at the subcellular level.
Plant Biol. (Stuttg.) 12(1) , 88-97, (2010) The effect of treatment with benzothiadiazole (BTH) or l-2-oxothiazolidine-4-carboxylic acid (OTC), and their interaction with Plum pox virus (PPV) infection, on antioxidative metabolism of pea plants was studied at the subcellular level. PPV infection produc... |
|
|
Protective effect of a cysteine prodrug and antioxidant, L-2-oxothiazolidine-4-carboxylate, against ethanol-induced gastric lesions in rats.
Exp. Toxicol. Pathol. 64(3) , 233-7, (2012) Earlier studies have suggested an important role of glutathione (GSH) in cytoprotection against free radicals induced oxidative damage. This study reports gastroprotective effects of a cysteine precursor, L-2-oxothiazolidine-4-carboxylate (OTC), in experiment... |
|
|
Anti-fibrotic effects of L-2-oxothiazolidine-4-carboxylic acid via modulation of nuclear factor erythroid 2-related factor 2 in rats.
BMB Rep. 45(6) , 348-53, (2012) L-2-Oxothiazolidine-4-carboxylic acid (OTC) is a cysteine prodrug that maintains glutathione in tissues. The present study was designed to investigate anti-fibrotic and anti-oxidative effects of OTC via modulation of nuclear factor erythroid 2-related factor ... |