3-Bromo-7-nitro-1H-indazole
3-Bromo-7-nitro-1H-indazole structure
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Common Name | 3-Bromo-7-nitro-1H-indazole | ||
|---|---|---|---|---|
| CAS Number | 74209-34-0 | Molecular Weight | 242.030 | |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 437.3±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H4BrN3O2 | Melting Point | 175-185 °C | |
| MSDS | USA | Flash Point | 218.3±23.2 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Metaplastic effects of subanesthetic ketamine on CA1 hippocampal function.
Neuropharmacology 86 , 273-81, (2014) Ketamine is a non-competitive N-methyl-d-aspartate receptor (NMDAR) antagonist of interest in neuropsychiatry. In the present studies, we examined the effects of subanesthetic, low micromolar ketamine on excitatory postsynaptic potentials (EPSPs), population ... |
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Role of nitric oxide in traumatic brain injury in the rat.
J. Neurosurg. 89 , 807-818, (1998) Although nitric oxide (NO) has been shown to play an important role in the pathophysiological process of cerebral ischemia, its contribution to the pathogenesis of traumatic brain injury (TBI) remains to be clarified. The authors investigated alterations in c... |
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7-Nitro indazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase.
Life Sci. 57 , PL131-PL135, (1995) The effect of 7-nitro indazole (7-NI) and a range of substituted indazole derivatives on nitric oxide synthase (NOS) enzyme activity in homogenates of rat cerebellum, bovine endothelial cells and lung from endotoxin-pretreated rats was investigated. 3-bromo 7... |
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The role of nitric oxide in the pathophysiology of thromboembolic stroke in the rat.
Brain Res. 759 , 32-40, (1997) Although nitric oxide (NO) has been shown to play an important role in the pathophysiology of cerebral ischemia, its contribution to the pathogenesis of experimentally induced thromboembolic stroke is unknown. In this study, we pharmacologically manipulated N... |
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Neuroprotective effects of the antioxidant LY231617 and NO synthase inhibitors in global cerebral ischaemia.
Brain Res. 760 , 170-178, (1997) Recent studies have shown that the novel antioxidant LY231617 protects against ischaemia-induced neuronal damage in rat models of global cerebral ischaemia. In the present studies we have examined the effects of LY231617 in the gerbil model of global cerebral... |
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S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease.
Molecular Neurodegeneration 8 , 29, (2013) Mutations in the gene encoding parkin, a neuroprotective protein with dual functions as an E3 ubiquitin ligase and transcriptional repressor of p53, are linked to familial forms of Parkinson's disease (PD). We hypothesized that oxidative posttranslational mod... |