1,1-Dimethylguanidine sulfate

1,1-Dimethylguanidine sulfate Structure
1,1-Dimethylguanidine sulfate structure
Common Name 1,1-Dimethylguanidine sulfate
CAS Number 598-65-2 Molecular Weight 185.20200
Density N/A Boiling Point 104.7ºC at 760 mmHg
Molecular Formula C3H11N3O4S Melting Point 300 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 17.1ºC
Symbol GHS07
GHS07
Signal Word Warning

Engineering of indole-based tethered biheterocyclic alkaloid meridianin into β-carboline-derived tetracyclic polyheterocycles via amino functionalization/6-endo cationic π-cyclization.

Beilstein J. Org. Chem. 8 , 1901-8, (2012)

A mild, efficient and versatile method has been developed for the construction of a functionalized natural product, meridianin, and its post conversion to pyrimido-β-carboline by cationic π- cyclization. The strategy involves the introduction of an amino grou...

Interactions of guanidine and a related compound with potassium channels in frog myelinated nerve fibre.

Receptors Channels 1(3) , 181-91, (1993)

The effects of guanidine and dimethyl guanidine were studied on current- and voltage-clamped nodes of Ranvier, to determine the electrophysiological basis for the guanidine-induced increase in neurotransmitter release. When added to the external solution, gua...

Effects of 1,1-dimethylguanidine administration on blood pressure, heart rate and renal sympathetic nerve activity in normotensive and spontaneously hypertensive rats.

Acta Physiol. Scand. 159(1) , 1-6, (1997)

1,1-dimethylguanidine (DMG) is an endogenous nitric oxide (NO) synthesis inhibitor. This study investigates the effects of exogenous DMG administration, in anaesthetized spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Mean blood pressure (M...

Reaction of 3-deoxypentosulose with N-methyl- and N,N-dimethylguanidine as model reagents for protein-bound arginine and for creatine.

Z. Lebensm. Unters. Forsch. 201(4) , 381-6, (1995)

Deoxyosones are established key-intermediates in Maillard processes. Due to their dicarbonyl structure, they undergo condensation to form heterocyclic compounds with guanidine derivatives. In biological systems, guanidino functions are present in protein-boun...

Inactivation of nitric oxide synthase isoforms by diaminoguanidine and NG-amino-L-arginine.

Arch. Biochem. Biophys. 325(2) , 227-34, (1996)

Diaminoguanidine (DAG) and NG-amino-L-arginine each produced a time- and concentration-dependent inactivation of the citrulline-forming activity of all three NOS isoforms. DAG inactivates both the NADPH-oxidase and the citrulline-forming activities of GH3 pit...

Structure-activity relationship between guanidine alkyl derivatives and norepinephrine release: site(s) and mechanism(s) of action.

J. Pharmacol. Exp. Ther. 230(3) , 710-7, (1984)

The effect of guanidine alkyl derivatives on the evoked release of [3H]norepinephrine [( 3H]NE) from spleen strips was examined. Guanidine, methyl guanidine and N,N-dimethyl guanidine all enhanced the field-stimulated release of [3H]NE 2- to 3-fold, whereas N...

Guanidine derivatives used as peroxide activators for bleaching cellulosic textiles. Cai JY and Evans DJ.

Color. Technol. 123(2) , 115-18, (2007)