B02
B02 structure
|
Common Name | B02 | ||
|---|---|---|---|---|
| CAS Number | 1290541-46-6 | Molecular Weight | 339.39000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H17N3O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A novel role for non-ubiquitinated FANCD2 in response to hydroxyurea-induced DNA damage.
Oncogene 35 , 22-34, (2016) Fanconi anemia (FA) is a genetic disease of bone marrow failure, cancer susceptibility, and sensitivity to DNA crosslinking agents. FANCD2, the central protein of the FA pathway, is monoubiquitinated upon DNA damage, such as crosslinkers and replication block... |
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Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function.
PLoS Genet. 9 , e1003910, (2013) In checkpoint-deficient cells, DNA double-strand breaks (DSBs) are produced during replication by the structure-specific endonuclease MUS81. The mechanism underlying MUS81-dependent cleavage, and the effect on chromosome integrity and viability of checkpoint ... |
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