Quinestrol
Quinestrol structure
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Common Name | Quinestrol | ||
|---|---|---|---|---|
| CAS Number | 152-43-2 | Molecular Weight | 364.520 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 502.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C25H32O2 | Melting Point | 107 - 108ºC | |
| MSDS | Chinese USA | Flash Point | 218.8±24.4 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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The bioaccumulation and biotransformation of synthetic estrogen quinestrol in crucian carp.
Aquat. Toxicol. 155 , 84-90, (2014) The occurrence and fate of endocrine disrupting chemicals (EDCs) in aquatic species have attracted close attention during the last decades. In this study, the bioaccumulation and biotransformation of synthetic estrogen quinestrol, one of the typical EDCs, in ... |
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Photodegradation of quinestrol in waters and the transformation products by UV irradiation.
Chemosphere 89(11) , 1419-25, (2012) Quinestrol is synthetic estrogen used in contraceptive and hormone replacement therapy and occasionally for treating breast cancer and prostate cancer. It can make its way into the environment through sewage discharge and waste disposal produced by human excr... |
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Effects of quinestrol on reproductive hormone expression, secretion, and receptor levels in female Mongolian gerbils (Meriones unguiculatus).
Theriogenology 77(6) , 1223-31, (2012) Quinestrol, a synthetic estrogen with marked estrogenic effects and prolonged activity, has potential as a contraceptive for Mongolian gerbils. The objective of this study was to describe the effects of quinestrol on reproductive hormone expression, secretion... |
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Quinestrol treatment induced testicular damage via oxidative stress in male Mongolian gerbils (Meriones unguiculatus).
Exp. Anim. 60(5) , 445-53, (2011) The hypothesis that quinestrol exerts testicular damage via oxidative stress was investigated in male gerbils using a daily oral gavage of 3.5 mg/kg body weight for 2 weeks (the multidose-treated group) or 35 mg/kg body weight (the single-dose-treated group).... |
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Behavioral evaluation of quinestrol as a sterilant in male Brandt's voles.
Physiol. Behav. 104(5) , 1024-30, (2011) The theoretical, ecological, physiological, and mathematical aspects of fertility control in mammals have already been well studied, but little attention has been given to the behavioral effects, especially in rodents. We investigated the effects of quinestro... |
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Subfertile effects of quinestrol and levonorgestrel in male rats.
Reprod. Fertil. Dev. 24(2) , 297-308, (2012) The contraceptive regimen consisting of levonorgestrel and quinestrol (EP-1) has been shown to be effective in several types of wild rodents. In the present study, we investigated the effect of EP-1 and its two components on fertility and spermatogenesis to e... |
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Combined effects of levonorgestrel and quinestrol on reproductive hormone levels and receptor expression in females of the Mongolian gerbil (Meriones unguiculatus).
Zoolog. Sci. 29(1) , 37-42, (2012) The effects of treatment with a combination of levonorgestrel and quinestrol (EP-1; ratio of 2:1) on reproductive hormone levels and the expression of their receptors in female Mongolian gerbils were examined. We show that serum follicle-stimulating hormone (... |
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Effects of quinestrol as a contraceptive in mongolian gerbils (Meriones unguiculatus).
Exp. Anim. 60(5) , 489-96, (2011) The contraceptive effects of quinestrol in Mongolian gerbils were examined. The results showed that body weight significantly increased after quinestrol treatment, except in the group that received the highest dose. The gonadosomatic index of ovaries decrease... |
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Low-dose hormone therapy in postmenopausal women in China.
Climacteric 13(6) , 544-52, (2010) To review the experience of menopausal symptoms and low-dose hormone therapy (HT) in postmenopausal women in China.Literature review and critical summaries of available prospective, clinical trials (randomized, controlled trials, RCTs).Chinese women experienc... |
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Development and validation of a HPLC method for determination of levonorgestrel and quinestrol in rat plasma.
Biomed. Chromatogr. 24(7) , 706-10, (2010) Levonorgestrel and quinestrol, commonly known as EP-1, has long been used in the control of wild rodents. Up to the present time, however, no method for simultaneous quantification of levonorgestrel and quinestrol in rat plasma has been reported. In the prese... |