Oleamide
Oleamide structure
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Common Name | Oleamide | ||
|---|---|---|---|---|
| CAS Number | 301-02-0 | Molecular Weight | 281.477 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 433.3±24.0 °C at 760 mmHg | |
| Molecular Formula | C18H35NO | Melting Point | 70°C | |
| MSDS | Chinese USA | Flash Point | 215.9±22.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Prymnesium parvum revisited: relationship between allelopathy, ichthyotoxicity, and chemical profiles in 5 strains.
Aquat. Toxicol. 157 , 159-66, (2014) Bioassay-guided discovery of ichthyotoxic algal compounds using in vivo fish assays is labor intensive, costly, and highly regulated. Since the mode of action of most known algal-mediated fish-killing toxins is damage to the cell membranes in the gills, vario... |
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Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activity.
PLoS ONE 10(3) , e0118512, (2015) Despite the ever-increasing number of patients with dementia worldwide, fundamental therapeutic approaches to this condition have not been established. Epidemiological studies suggest that intake of fermented dairy products prevents cognitive decline in the e... |
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Connexin 43 expressed in endothelial cells modulates monocyte‑endothelial adhesion by regulating cell adhesion proteins.
Mol. Med. Report. 12 , 7146-52, (2015) Adhesion between circulating monocytes and vascular endothelial cells is a key initiator of atherosclerosis. In our previous studies, it was demonstrated that the expression of connexin (Cx)43 in monocytes modulates cell adhesion, however, the effects of the ... |
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Role of gap junction intercellular communication in testicular leydig cell apoptosis induced by oxaliplatin via the mitochondrial pathway.
Oncol. Rep. 33(1) , 207-14, (2014) Prostate cancer is a frequent cause of male death in the Western world. Relatively few genetic alterations have been identified, likely owing to disease heterogeneity. Here, we show that the transcription factor JUNB/AP-1 limits prostate cancer progression. J... |
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The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications.
J. Med. Chem. 48 , 5059-87, (2005)
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Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors.
J. Med. Chem. 51 , 7327-43, (2008)
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Anti-angiogenesis therapy and gap junction inhibition reduce MDA-MB-231 breast cancer cell invasion and metastasis in vitro and in vivo.
Sci. Rep. 5 , 12598, (2015) Cancer cells secrete VEGF, which plays a key role in their growth, invasion, extravasation and metastasis. Direct cancer cell-endothelial cell interaction, mediated by gap junctions, is of critical importance in the extravasation process. In this study, we ev... |
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Dysfunction in gap junction intercellular communication induces aberrant behavior of the inner cell mass and frequent collapses of expanded blastocysts in mouse embryos.
J. Assist. Reprod. Genet. 32 , 969-76, (2015) We investigated the role of gap junctions (GJs) in embryological differentiation, and observed the morphological behavior of the inner cell mass (ICM) by time-lapse movie observation (TLM) with gap junction inhibitors (GJis).ICR mouse embryos were exposed to ... |
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The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation.
Bone 44 , 80-6, (2009) Gap junctions (GJs) are membrane-spanning channels that facilitate intercellular communication by allowing small signaling molecules (e.g. calcium ions, inositol phosphates, and cyclic nucleotides) to pass from cell to cell. Over the past two decades, many st... |
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Endothelial connexin 32 regulates tissue factor expression induced by inflammatory stimulation and direct cell-cell interaction with activated cells.
Atherosclerosis 236(2) , 430-7, (2014) Endothelial cell (EC) interacts with adjacent EC through gap junction, and abnormal expression or function of Cxs is associated with cardiovascular diseases. In patients with endothelial dysfunction, the up-regulation of tissue factor (TF) expression promotes... |