Oleamide

Modify Date: 2024-01-02 09:13:22

Oleamide Structure
Oleamide structure
 Common Name Oleamide
CAS Number 301-02-0 Molecular Weight 281.477
Density 0.9±0.1 g/cm3 Boiling Point 433.3±24.0 °C at 760 mmHg
Molecular Formula C18H35NO Melting Point 70°C
MSDS Chinese USA Flash Point 215.9±22.9 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Oleamide


Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.

 Names

Name oleamide
Synonym More Synonyms

 Oleamide Biological Activity

Description Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Oleamide accumulates in the cerebrospinal fluid (CSF) of rats after six hours of sleep deprivation and induces sleep in naive rats and mice. Inhibition of the primary catabolic enzyme of oleamide (fatty acid amide hydrolase) by trifluoromethyl-octadecenone reduces sleep latency and increases total sleep time when given centrally to rats and peripherally to mice[1]
References

[1]. Mendelson WB, et al. The hypnotic actions of the fatty acid amide, oleamide. Neuropsychopharmacology. 2001 Nov;25(5 Suppl):S36-9.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 433.3±24.0 °C at 760 mmHg
Melting Point 70°C
Molecular Formula C18H35NO
Molecular Weight 281.477
Flash Point 215.9±22.9 °C
Exact Mass 281.271851
PSA 43.09000
LogP 6.75
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.469
Storage condition −20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H317-H319-H335
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 1
HS Code 2924199090

 Synthetic Route

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles45

More Articles
Prymnesium parvum revisited: relationship between allelopathy, ichthyotoxicity, and chemical profiles in 5 strains.

Aquat. Toxicol. 157 , 159-66, (2014)

Bioassay-guided discovery of ichthyotoxic algal compounds using in vivo fish assays is labor intensive, costly, and highly regulated. Since the mode of action of most known algal-mediated fish-killing...

Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activity.

PLoS ONE 10(3) , e0118512, (2015)

Despite the ever-increasing number of patients with dementia worldwide, fundamental therapeutic approaches to this condition have not been established. Epidemiological studies suggest that intake of f...

Connexin 43 expressed in endothelial cells modulates monocyte‑endothelial adhesion by regulating cell adhesion proteins.

Mol. Med. Report. 12 , 7146-52, (2015)

Adhesion between circulating monocytes and vascular endothelial cells is a key initiator of atherosclerosis. In our previous studies, it was demonstrated that the expression of connexin (Cx)43 in mono...

 Synonyms

(9Z)-9-Octadecenamide
oleicacidamide-heptaglycolether
9-Octadecenamide, (9Z)-
9-Octadecenimidic acid, (9Z)-
Oleic acid amide
9-Octadecenoic acid, amide (cis)
Adogen 73
EINECS 206-103-9
9-Octadecenamide, (Z)- (9CI)
Amide O
OLEAMID
Armid O
MFCD00053638
Slip-eze
(9Z)-9-Octadecenimidic acid
AMD-O
(Z)-9-Octadecenamide
9-Octadecenamide, (Z)-
cis-9,10-Octadecenoamide cis-9-Octadecenamide Oleic acid amide
cis-9,10-Octadecenoamide
cis-9-octadecenamide
Oleamide
9-cis-Oleamide
(9Z)-Octadec-9-enamide
Plastic additive 20
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oleamide
3322-62-1
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OLEAMIDE DEA
5299-69-4
OLEAMIDE MEA
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cis-oleamide
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Oleamide MIPA
111-05-7
oleamide mipa
54375-42-7
PEG-3 OLEAMIDE
26027-37-2
trans-oleamide
4303-70-2
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Chemsrc provides Oleamide(CAS#:301-02-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Oleamide are included as well.>> amp version: Oleamide

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