Ethyl salicylate

Ethyl salicylate Structure
Ethyl salicylate structure
Common Name Ethyl salicylate
CAS Number 118-61-6 Molecular Weight 166.174
Density 1.2±0.1 g/cm3 Boiling Point 234.4±13.0 °C at 760 mmHg
Molecular Formula C9H10O3 Melting Point 1 °C(lit.)
MSDS Chinese USA Flash Point 107.2±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Evaluation of injection methods for fast, high peak capacity separations with low thermal mass gas chromatography.

J. Chromatogr. A. 1392 , 82-90, (2015)

Low thermal mass gas chromatography (LTM-GC) was evaluated for rapid, high peak capacity separations with three injection methods: liquid, headspace solid phase micro-extraction (HS-SPME), and direct vapor. An Agilent LTM equipped with a short microbore capil...

Occurrence and spatial distribution of EDCs and related compounds in waters and sediments of Iberian rivers.

Sci. Total Environ. 503-504 , 69-86, (2015)

The environmental presence of chemicals capable of affecting the endocrine system has become a matter of scientific and public concern after certain endocrine disruptor compounds (EDCs) have been detected in the aquatic environment. In this work, 31 different...

Analysis of endocrine disrupters and related compounds in sediments and sewage sludge using on-line turbulent flow chromatography-liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1352 , 29-37, (2014)

A novel fully automated method based on dual column switching using turbulent flow chromatography followed by liquid chromatography coupled to tandem mass spectrometry (TFC-LC-MS/MS) was applied for the determination of endocrine disruptors (EDCs) and related...

On-line reaction monitoring by extractive electrospray ionisation.

Rapid Commun. Mass Spectrom. 25(10) , 1445-51, (2011)

The design and development of a novel extractive electrospray ionisation (EESI) device for on-line reaction monitoring is described. The EESI apparatus uses a secondary, grounded nebuliser to produce an analyte aerosol and a Venturi pump is then used to trans...

Encapsulation of methyl and ethyl salicylates by beta-cyclodextrin HPLC, UV-vis and molecular modeling studies.

J. Pharm. Biomed. Anal. 48(3) , 969-73, (2008)

The complexation of methyl salicylate (MS) and ethyl salicylate (ES), non-steroidal analgesic, anti-inflammatory and antirrheumatic drugs with beta-cyclodextrin (betaCD) has been studied from thermodynamic and structural points of view. The complexation with ...

Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation.

J. Pharm. Biomed. Anal. 60 , 51-8, (2012)

Capsaicinoids, salicylic acid, methyl and ethyl salicylate, glycol monosalicylate, camphor and l-menthol are widely used in topical formulations to relieve local pain. For each separate compound or simple mixtures, quantitative analysis methods are reported. ...

Levels of mint and wintergreen flavorants: smokeless tobacco products vs. confectionery products.

Food Chem. Toxicol. 48(2) , 755-63, (2010)

Nicotine and flavorant compound levels were measured in 10 "mint"-related sub-brands and 8 "wintergreen" sub-brands of smokeless tobacco (SLT). Also analyzed were "mint"-related and "wintergreen" confectionery products. Of the "mint" SLT, "Timberwolf Packs Mi...

Simultaneous quantitative analysis of methyl salicylate, ethyl salicylate and salicylic acid from biological fluids using gas chromatography-mass spectrometry.

J. Chromatogr. B. Biomed. Sci. Appl. 718(1) , 69-75, (1998)

A gas chromatographic-mass spectrometric (GC-MS) assay was developed for the quantitative analysis of methyl salicylate (MeS), ethyl salicylate (ES) and salicylic acid (SA) from biological fluids. The method was validated from 100-microl rat liver homogenate ...

Percutaneous penetration and skin metabolism of ethylsalicylate-containing agent, TU-2100: in-vitro and in-vivo evaluation in guinea pigs.

J. Control. Release 79(1-3) , 113-22, (2002)

The aim of this study was to investigate the percutaneous penetration and dermal metabolism of a new potential anti-acne prodrug--TU-2100 [bis(o-carboxyphenyl ethyl ester)nonanedioate] in guinea pigs. The fluxes of this agent through excised skin after applic...

Some observations on the pharmacology of 'deep-heat', a topical rubifacient.

Ann. Rheum. Dis. 43(3) , 411-5, (1984)

A topically applied rubifacient delivered by aerosol (Deep-Heat) was studied. After spray application to the forearms of volunteers, without massage, the erythema produced was measured by thermography and correlated with the concentration of 2 salicylate comp...