![]() Sodium caprylate [USAN] structure
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Common Name | Sodium caprylate [USAN] | ||
---|---|---|---|---|
CAS Number | 1984-06-1 | Molecular Weight | 166.193 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C8H15NaO2 | Melting Point | 245 ℃ (dec.) | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
![]() GHS07 |
Signal Word | Warning |
Rapid dissolution of propofol emulsions under sink conditions.
Int. J. Pharm. 481(1-2) , 47-55, (2015) Pain accompanying intravenous injections of propofol is a major problem in anesthesia. Pain is ascribed to the interaction of propofol with the local vasculature and could be impacted by rapid dissolution of the emulsion formulation to release the drug. In th... |
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Desorption atmospheric pressure photoionization high-resolution mass spectrometry: a complementary approach for the chemical analysis of atmospheric aerosols.
Rapid Commun. Mass Spectrom. 29 , 1233-41, (2015) On-line chemical characterization methods of atmospheric aerosols are essential to increase our understanding of physicochemical processes in the atmosphere, and to study biosphere-atmosphere interactions. Several techniques, including aerosol mass spectromet... |
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A novel suspension formulation enhances intestinal absorption of macromolecules via transient and reversible transport mechanisms.
Pharm. Res. 31(8) , 2010-21, (2014) Medium chain fatty acid salts promote absorption by increasing paracellular permeability of the intestinal epithelium. Novel oily suspension (OS) formulation disperses a powder containing sodium caprylate and macromolecules such as octreotide or fluorescent d... |
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The role of amphiphilicity and negative charge in glycoprotein 41 interactions in the hydrophobic pocket.
J. Med. Chem. 52 , 4338-44, (2009) The hydrophobic pocket within the coiled coil domain of HIV-1 gp41 is considered to be a hot-spot suitable for small molecule intervention of fusion, although so far it has yielded only microM inhibitors. Previous peptide studies have identified specific hydr... |
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Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia.
J. Clin. Invest. 124(12) , 5175-90, (2014) Nonalcoholic fatty liver disease (NAFLD) spectrum disorders affect approximately 1 billion individuals worldwide. However, the drivers of progressive steatohepatitis remain incompletely defined. Ketogenesis can dispose of much of the fat that enters the liver... |
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Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery.
Int. J. Pharm. 486 , 232-41, (2015) Intravenous injections of propofol emulsions are accompanied by pain likely due to the interaction of the dissolved drug with endothelial cells of the vasculature. It is commonly hypothesized that reducing the aqueous phase concentration of propofol could red... |
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Rates of fatty acid oxidations by P450 compound I are pH dependent.
ChemBioChem. 13(14) , 2061-4, (2012) The rates of oxidation of fatty acids by CYP119 compound I were dependent on the pH of the medium. The plot shows log k values for reactions of acids as a function of pH, where the slopes indicate mixed third-order and fourth-order dependence on base concentr... |
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Safety of medium-chain triglycerides used as an intraocular tamponading agent in an experimental vitrectomy model rabbit.
Retina (Philadelphia, Pa.) 33(1) , 217-23, (2013) To evaluate safety of medium-chain triglycerides used as a possible intraocular tamponading agent.A 20-gauge pars plana vitrectomy was performed in the right eye of 28 rabbits. An ophthalmologic examination was performed every week until rabbits were killed. ... |
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Biosynthesis and properties of medium-chain-length polyhydroxyalkanoates with enriched content of the dominant monomer.
Biomacromolecules 13(9) , 2926-32, (2012) When grown in a nonanoic acid-limited chemostat at a dilution rate of 0.25 h(-1), Pseudomonas putida KT2440 produced poly(3-hydroxynonanoate-co-3-hydroxyheptanoate) containing 68 mol % 3-hydroxynonanoate (C9) and 32 mol % 3-hydroxyheptanoate (C7). Under the s... |
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Purification of human immunoglobulins A, G and M from Cohn fraction II/III by small peptide affinity chromatography.
J. Chromatogr. A. 1262 , 169-79, (2012) This work describes attempts to purify human IgG, IgA and IgM from Cohn fraction II/III using HWRGWV affinity peptide resin. The effects of peptide density and different elution additives on recovery of the three antibodies were investigated. At low peptide d... |