Gastric Inhibitory Polypeptide (human)
Gastric Inhibitory Polypeptide (human) structure
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Common Name | Gastric Inhibitory Polypeptide (human) | ||
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| CAS Number | 100040-31-1 | Molecular Weight | 4983.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C226H338N60O66S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Long-term persistence of hormonal adaptations to weight loss.
N. Engl. J. Med. 365 , 1597-1604, (2011) After weight loss, changes in the circulating levels of several peripheral hormones involved in the homeostatic regulation of body weight occur. Whether these changes are transient or persist over time may be important for an understanding of the reasons behi... |
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Pleiotropic effects of GIP on islet function involve osteopontin.
Diabetes 60 , 2424-2433, (2011) The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of ... |
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Gastric inhibitory polypeptide and its receptor are expressed in the central nervous system and support neuronal survival.
Cent. Nerv. Syst. Agents Med. Chem. 11 , 210-222, (2011) The development of neuronal apoptosis depends on an intrinsic transcriptional program. By DNA microarray technology, we have previously implicated a number of genes in different paradigms of neuronal apoptosis. In the present study, we investigated the spatio... |
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The isolation and sequencing of human gastric inhibitory peptide (GIP).
FEBS Lett. 172 , 142, (1984) Human GIP 1-42 and fragments of human GIP corresponding to GIP 10-42, GIP 11-42, and GIP 17-42 were isolated from acid-ethanol extracts of human small intestines with the aid of an anti-GIP serum specific for the extreme C-terminal portion of the GIP molecule... |
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Insulin modulates glucose-dependent insulinotropic polypeptide (GIP) secretion from enteroendocrine K cells in rats.
Biol. Chem. 392 , 909-918, (2011) Effects of insulin excess and deficiency on glucose-dependent insulinotropic polypeptide (GIP) was examined in rats following insulinoma transplantation or streptozotocin (STZ) administration. Over 14 days, food intake was increased (p < 0.001) in both groups... |
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Synthesis of a 42 residue peptide corresponding to the entire amino acid sequence of human GIP.
Chem. Pharm. Bull. 33 , 3578, (1985)
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Diabetes remission after bariatric surgery: is it just the incretins? Laferrère B.
Int. J. Obes. 35 , S22-25, (2011)
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