HUMAN VEGF165
HUMAN VEGF165 structure
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Common Name | HUMAN VEGF165 | ||
|---|---|---|---|---|
| CAS Number | 127464-60-2 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.
Int. J. Biochem. Cell Biol. 68 , 128-38, (2015) Peroxidases are heme-containing enzymes released by activated immune cells at sites of inflammation. To-date their functional role in human health has mainly been limited to providing a mechanism for oxidative defence against invading bacteria and other patho... |
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EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF.
Oncotarget 6 , 9766-80, (2015) EMMPRIN/CD147 is mainly known for its protease inducing function but a role in promoting tumor angiogenesis has also been demonstrated. This study provides evidence that EMMPRIN is a new coreceptor for the VEGFR-2 tyrosine kinase receptor in both endothelial ... |
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Cecal succinate elevated by some dietary polyphenols may inhibit colon cancer cell proliferation and angiogenesis.
J. Agric. Food Chem. 62(24) , 5589-94, (2014) This study demonstrated that 0.5% dietary rutin, ellagic acid, or curcumin markedly increased cecal succinate levels in rats fed a high-fat diet, whereas catechin, caffeic acid, and quercetin did not. Other organic acids were modestly or hardly affected by po... |
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Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells.
Biochim. Biophys. Acta 1840(12) , 3483-93, (2014) Leptin, 16kDa product of obese gene, is adipocytokine playing critical role in regulation of body weight. In recent years, leptin is also defined as potent angiogenic factor involving in tumorigenesis, angiogenesis, and metastasis. However, it is unknown whet... |
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Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples.
Exp. Hematol. 42(9) , 816-25, (2014) Induced pluripotent stem cells (iPS) derived from disease cells are expected to provide a new experimental material, especially for diseases from which samples are difficult to obtain. In this study, we generated iPS from samples from patients with primary an... |
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The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation.
PLoS ONE 10(4) , e0124259, (2015) Contact inhibition of cell movement and proliferation is critical for proper organogenesis and tissue remodeling. We show here a novel regulatory mechanism for this contact inhibition using cultured vascular endothelial cells. When the cells were confluently ... |
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Association between microalbuminuria predicting in-stent restenosis after myocardial infarction and cellular senescence of endothelial progenitor cells.
PLoS ONE 10(4) , e0123733, (2015) Relationship between microalbuminuria and worse outcome of coronary artery disease patients is discussed, but its underlying pathophysiological mechanism remains unclear. We investigated the role of microalbuminuria to the function of endothelial progenitor c... |
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Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model.
Eye (Lond.) 29(4) , 561-8, (2015) To determine intraocular pharmacokinetic properties of intravitreally injected vascular endothelial growth factor (VEGF)-Trap in a rabbit model.VEGF-Trap was intravitreally injected in 18 rabbit eyes. Eyes were enucleated 1 h and 1, 2, 5, 14, and 30 days afte... |
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The effect of AMA0428, a novel and potent ROCK inhibitor, in a model of neovascular age-related macular degeneration.
Invest. Ophthalmol. Vis. Sci. 56(2) , 1335-48, (2015) Rho kinase (ROCK) is associated with VEGF-driven angiogenesis, as well as with inflammation and fibrosis. Therefore, the effect of AMA0428, a novel ROCK inhibitor, was studied in these processes, which highly contribute to the pathogenesis of neovascular AMD.... |
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Evaluation of a new recombinant oncolytic vaccinia virus strain GLV-5b451 for feline mammary carcinoma therapy.
PLoS ONE 9(8) , e104337, (2014) Virotherapy on the basis of oncolytic vaccinia virus (VACV) infection is a promising approach for cancer therapy. In this study we describe the establishment of a new preclinical model of feline mammary carcinoma (FMC) using a recently established cancer cell... |