Alliin
Alliin structure
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Common Name | Alliin | ||
|---|---|---|---|---|
| CAS Number | 556-27-4 | Molecular Weight | 177.221 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 416.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C6H11NO3S | Melting Point | 165ºC | |
| MSDS | Chinese USA | Flash Point | 205.5±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Metabolism, excretion, and pharmacokinetics of S-allyl-L-cysteine in rats and dogs.
Drug Metab. Dispos. 43(5) , 749-55, (2015) The metabolism, excretion, and pharmacokinetics of S-allyl-l-cysteine (SAC), an active key component of garlic supplements, were examined in rats and dogs. A single dose of SAC was administered orally or i.v. to rats (5 mg/kg) and dogs (2 mg/kg). SAC was well... |
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Combination of aqueous two-phase extraction and cation-exchange chromatography: New strategies for separation and purification of alliin from garlic powder
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 60-7, (2014) In this study, a two-step process combining aqueous two-phase extraction (ATPE) with chromatography was developed for extraction and purification of alliin from garlic powder. The partition coefficient and yield value of alliin in different types of aqueous t... |
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Fluorescent magnetic iron oxide nanoparticles for cardiac precursor cell selection from stromal vascular fraction and optimization for magnetic resonance imaging.
Int. J. Nanomedicine 10 , 711-26, (2015) Fluorescent magnetic iron oxide nanoparticles have been used to label cells for imaging as well as for therapeutic purposes. The purpose of this study was to modify the approach to develop a nanoprobe for cell selection and imaging with a direct therapeutic t... |
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Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells.
PLoS ONE 9(11) , e113531, (2014) Aged garlic extract (AGE) is widely used as a dietary supplement, and is claimed to promote human health through anti-oxidant/anti-inflammatory activities with hypolipidemic, antiplatelet and neuroprotective effects. Prior studies of AGE have mainly focused o... |
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Molecular characterization of ongoing enzymatic reactions in raw garlic cloves using extractive electrospray ionization mass spectrometry.
Anal. Chem. 87(5) , 2878-83, (2015) Characterization of enzymatic reactions occurring in untreated biological samples is of increasing interest. Herein, the chemical conversion of alliin to allicin, catalyzed by allinase, in raw garlic cloves has been followed in vivo by internal extractive ele... |
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S-allyl cysteine alleviates nonsteroidal anti-inflammatory drug-induced gastric mucosal damages by increasing cyclooxygenase-2 inhibition, heme oxygenase-1 induction, and histone deacetylation inhibition.
J. Gastroenterol. Hepatol. 29 Suppl 4 , 80-92, (2014) Nonsteroidal anti-inflammatory drugs (NSAIDs), the most highly prescribed drugs in the world for the treatment of pain, inflammation, and fever, are associated with gastric mucosal damages including ulcer directly or indirectly. This study was aimed to docume... |
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Aggregates of mutant CFTR fragments in airway epithelial cells of CF lungs: new pathologic observations.
J. Cyst. Fibros. 14(2) , 182-93, (2015) Cystic fibrosis (CF) is caused by a mutation in the CF transmembrane conductance regulator (CFTR) gene resulting in a loss of Cl(-) channel function, disrupting ion and fluid homeostasis, leading to severe lung disease with airway obstruction due to mucus plu... |
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Agar films containing silver nanoparticles as new supports for electromembrane extraction.
Anal. Bioanal. Chem 407(5) , 1519-25, (2015) A new support containing silver nanoparticles to assist electromembrane extraction (EME) procedures is proposed. For the first time, synthesized agar films containing silver nanoparticles (AgNPs) have been used as a support for liquid membranes in EME. Agaros... |
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Effects of coformers on phase transformation and release profiles of carbamazepine cocrystals in hydroxypropyl methylcellulose based matrix tablets.
Int. J. Pharm. 479(1) , 118-28, (2015) The aim of this study was to investigate the effects of coformers on phase transformation and release profiles of carbamazepine (CBZ) cocrystals in hydroxypropyl methylcellulose (HPMC) based matrix tablets. It has been found that selection of different coform... |
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Chloroquine differentially modulates inflammatory cytokine expression in RAW 264.7 cells in response to inactivated Staphylococcus aureus.
Inflammation 38(2) , 745-55, (2015) The anti-inflammatory property of chloroquine (CQ) has long been recognized. This study aimed to investigate the effect of CQ on proinflammatory cytokine expression in RAW 264.7 macrophages stimulated with heat-inactivated Staphylococcus aureus cells (SAC). T... |