3-Bromo-4-methylpyridine

3-Bromo-4-methylpyridine Structure
3-Bromo-4-methylpyridine structure
Common Name 3-Bromo-4-methylpyridine
CAS Number 3430-22-6 Molecular Weight 172.023
Density 1.5±0.1 g/cm3 Boiling Point 198.8±20.0 °C at 760 mmHg
Molecular Formula C6H6BrN Melting Point N/A
MSDS Chinese USA Flash Point 74.1±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Tricyclic pyridones as functionally selective human GABAA alpha 2/3 receptor-ion channel ligands.

Bioorg. Med. Chem. Lett. 14(7) , 1679-82, (2004)

A series of tricyclic pyridones has been evaluated as benzodiazepine site ligands with functional selectivity for the alpha(3) over the alpha(1) containing subtype of the human GABA(A) receptor ion channel. This investigation led to the identification of a hi...

Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters.

Bioorg. Med. Chem. Lett. 12(20) , 3009-13, (2002)

A detailed SAR study directed toward the optimization of pharmacokinetic parameters for analogues of L-791,943 is reported. The introduction of a soft metabolic site on this structure permitted the identification of L-826,141 as a potent phosphodiesterase typ...

Total synthesis of ascididemin via anionic cascade ring closure.

Chem. Commun. (Camb.) 48(72) , 9092-4, (2012)

A new and convergent synthesis of ascididemin is presented. Using an anionic cascade ring closure as the key step, this natural product is obtained in 45% overall yield in just 6 steps starting from 2'-fluoroacetophenone. This new approach was extended to the...

Condensed heteroaromatic ring systems. XV. Synthesis of pyranopyridinones from halopyridinecarbonitriles. Sakamoto T, et al.

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