Gonadorelin diacetate
Gonadorelin diacetate structure
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Common Name | Gonadorelin diacetate | ||
|---|---|---|---|---|
| CAS Number | 71447-49-9 | Molecular Weight | 1302.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C55H75N17O13.2C2H4O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Reduced melanocortin production causes sexual dysfunction in male mice with POMC neuronal insulin and leptin insensitivity.
Endocrinology 156(4) , 1372-85, (2015) Proopiomelanocortin (POMC)-derived peptides like α-melanocyte-stimulating hormone (MSH) substantially improve hepatic insulin sensitivity and regulate energy expenditure. Melanocortinergic agents are also powerful inducers of sexual arousal that are being inv... |
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Developmental programming: impact of prenatal testosterone excess on pre- and postnatal gonadotropin regulation in sheep.
Biogerontology 78 , 648-60, (2008) The goal of this study was to explore mechanisms that mediate hypersecretion of LH and progressive loss of cyclicity in female sheep exposed during fetal life to excess testosterone. Our working hypothesis was that prenatal testosterone excess, by its androge... |
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GnRH receptor and apoptotic signaling.
Vitam. Horm. 59 , 1-33, (2000) In addition to its hypophysiotropic action, gonadotropin-releasing hormone (GnRH) can modify activity in extrapituitary organs and peripheral tumors. GnRH analogs are the preferred treatment for advanced and even metastatic or recurring carcinomas in vivo and... |
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Pituitary and extrapituitary actions of gonadotrophin-releasing hormone and its analogues.
Hum. Reprod. 14 , 194-206, (1999) The hypothalamic decapeptide gonadotrophin-releasing hormone (GnRH) binds to high affinity receptors on pituitary gonadotrophs. These receptors mediate the effects of GnRH on secretion and synthesis of gonadotrophins. The GnRH receptor is coupled to Gq/G11, w... |
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Mechanism of GnRH receptor signaling: from the membrane to the nucleus.
Ann. Endocrinol. 60 , 79-88, (1999) The purpose of this review is to update the information concerning the intracellular effect of GnRH. Binding of GnRH to a G-protein coupled receptor leads to stimulation of Gq and/or G11 protein and to activation of phospholipase C beta. Inositol 1-4-5-tripho... |
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An inducible offense: carnivore morph tadpoles induced by tadpole carnivory.
Ecol. Evol. 5(7) , 1405-11, (2015) Phenotypic plasticity is commonplace, and plasticity theory predicts that organisms should often evolve mechanisms to detect and respond to environmental cues that accurately predict future environmental conditions. Here, we test this prediction in tadpoles o... |