3-Pyridineacrylic acid

3-Pyridineacrylic acid Structure
3-Pyridineacrylic acid structure
Common Name 3-Pyridineacrylic acid
CAS Number 19337-97-4 Molecular Weight 149.15
Density 1.3±0.1 g/cm3 Boiling Point 307.6±17.0 °C at 760 mmHg
Molecular Formula C8H7NO2 Melting Point 232-235ºC
MSDS Chinese USA Flash Point 139.8±20.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011)

Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids and esters such as methyl fumarate also interact with the r...