Ethylphosphonic acid

Ethylphosphonic acid Structure
Ethylphosphonic acid structure
Common Name Ethylphosphonic acid
CAS Number 6779-09-5 Molecular Weight 110.04900
Density N/A Boiling Point 260.5ºC at 760 mmHg
Molecular Formula C2H7O3P Melting Point 61-63 °C(lit.)
MSDS Chinese USA Flash Point 111.3ºC
Symbol GHS05
GHS05
Signal Word Danger

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: application to a pilot pharmacokinetic study in humans.

J. Pharm. Biomed. Anal. 105 , 39-45, (2015)

A high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, using hydrophilic interaction liquid chromatography (HILIC) chromatography for the analysis of fosfomycin in human plasma and urine, has been developed and validated. The pla...

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling.

Bioanalysis 7 , 2585-95, (2015)

Fosfomycin is an antibiotic of considerable interest for the treatment of infection by multidrug-resistant bacteria. Translating microsampling techniques into clinical PK studies may provide effective dosing information to improve patient outcomes and minimiz...

p-Tolyl isocyanate derivatization for analysis of CWC-related polar degradation products by mass spectrometry.

Anal. Bioanal. Chem 406(21) , 5093-102, (2014)

Most of the precursors and/or degradation products related to the Chemical Weapons Convention (CWC) are polar. Identification of these molecules in environmental samples provides clues regarding the alleged usage and/or synthesis of the parent toxic chemicals...

[Acyclic nucleotide analogues based on phosphonic acids].

Bioorg. Khim. 24(1) , 16-20, (1998)

The synthesis of novel nucleotide analogues on the basis of ethylphosphonic acid was described. A rigid structural element, an amide or a double bond, was characteristics of the compounds synthesized. The antiviral and cytotoxic activities of these compounds ...

A novel derivatization method for the determination of Fosfomycin in human plasma by liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometric detection via phase transfer catalyzed derivatization.

J. Chromatogr. A. 1332 , 1-7, (2014)

An analytical method employing novel sample preparation and liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometric detection (LC-APCI/MS) was developed for the determination of fosfomycin in human plasma. Sample prepara...