![]() 4-(4-aminophenyl)aniline structure
|
Common Name | 4-(4-aminophenyl)aniline | ||
---|---|---|---|---|
CAS Number | 92-87-5 | Molecular Weight | 184.237 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 402°C | |
Molecular Formula | C12H12N2 | Melting Point | 127-128 °C | |
MSDS | Chinese USA | Flash Point | 11 °C | |
Symbol |
![]() ![]() ![]() ![]() GHS02, GHS06, GHS08, GHS09 |
Signal Word | Danger |
Design and synthesis of a cell-permeable, drug-like small molecule inhibitor targeting the polo-box domain of polo-like kinase 1.
PLoS ONE 9(9) , e107432, (2014) Polo-like kinase-1 (Plk1) plays a crucial role in cell proliferation and the inhibition of Plk1 has been considered as a potential target for specific inhibitory drugs in anti-cancer therapy. Several research groups have identified peptide-based inhibitors th... |
|
Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins
Bioorg. Med. Chem. 17 , 896-904, (2009) This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the mole... |
|
Adhesive and migratory effects of phosphophoryn are modulated by flanking peptides of the integrin binding motif.
PLoS ONE 9(11) , e112490, (2014) Phosphophoryn (PP) is generated from the proteolytic cleavage of dentin sialophosphoprotein (DSPP). Gene duplications in the ancestor dentin matrix protein-1 (DMP-1) genomic sequence created the DSPP gene in toothed animals. PP and DMP-1 are phosphorylated ex... |
|
Quantitative activation-induced manganese-enhanced MRI reveals severity of Parkinson's disease in mice.
Sci. Rep. 5 , 12800, (2015) We demonstrate that activation-induced manganese-enhanced magnetic resonance imaging with quantitative determination of the longitudinal relaxation time (qAIM-MRI) reveals the severity of Parkinson's disease (PD) in mice. We first show that manganese ion-accu... |
|
Cortico-Cortical Connectivity Within Ferret Auditory Cortex.
J. Comp. Neurol. 523 , 2187-210, (2015) Despite numerous studies of auditory cortical processing in the ferret (Mustela putorius), very little is known about the connections between the different regions of the auditory cortex that have been characterized cytoarchitectonically and physiologically. ... |
|
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
J. Med. Chem. 50 , 742-8, (2007) The development of in silico and in vitro tools to estimate or predict the passive human skin permeation and distribution of new chemical entities, useful in dermal drug delivery, in absorption studies of toxic compounds, and in the cosmetics industry, is pre... |
|
Donor Heart Treatment With COMP-Ang1 Limits Ischemia-Reperfusion Injury and Rejection of Cardiac Allografts.
Am. J. Transplant. 15 , 2075-84, (2015) The major cause of death during the first year after heart transplantation is primary graft dysfunction due to preservation and ischemia-reperfusion injury (IRI). Angiopoietin-1 is a Tie2 receptor-binding paracrine growth factor with anti-inflammatory propert... |
|
GATA4 and GATA6 Knockdown During Luteinization Inhibits Progesterone Production and Gonadotropin Responsiveness in the Corpus Luteum of Female Mice.
Biol. Reprod. 93 , 133, (2015) The surge of luteinizing hormone triggers the genomic reprogramming, cell differentiation, and tissue remodeling of the ovulated follicle, leading to the formation of the corpus luteum. During this process, called luteinization, follicular granulosa cells beg... |
|
Cellular interaction of nontypeable Haemophilus influenzae triggers cytotoxicity of infected type II alveolar cells via apoptosis.
Pathog. Dis. 73(2) , 1-12, (2015) Nontypeable Haemophilus influenzae (NTHi) is an important cause of lower respiratory tract infections, resulting in exacerbations of chronic obstructive pulmonary disease (COPD). Despite its pathogenic potential, little is known regarding the role of intracel... |
|
SOCS genes expression during physiological and perturbed implantation in bovine endometrium.
Reproduction 148(6) , 545-57, (2014) In mammals, suppressor of cytokine signalling (CISH, SOCS1 to SOCS7) factors control signalling pathways involved in the regulation of numerous physiological processes including pregnancy. In order to gain new insights into the biological functions of SOCS in... |