Cinnamic acid
Cinnamic acid structure
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Common Name | Cinnamic acid | ||
|---|---|---|---|---|
| CAS Number | 140-10-3 | Molecular Weight | 148.159 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 265.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C9H8O2 | Melting Point | 133 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 189.5±9.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Analysis of initial reactions of MALDI based on chemical properties of matrixes and excitation condition.
J. Phys. Chem. B 116(32) , 9635-43, (2012) This investigation concerns the initial chemical reactions that affect the ionization of matrixes in matrix-assisted laser desorption/ionization (MALDI). The study focuses on the relaxations of photon energy that occur on a comparable time scale to that of io... |
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Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
Bioorg. Med. Chem. 17 , 5219-28, (2009) In the light of known HDAC inhibitors, 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop the structure-activity relationships of carboxylic acid HDA... |
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Metabolic engineering of Escherichia coli for the synthesis of the plant polyphenol pinosylvin.
Appl. Environ. Microbiol. 81(3) , 840-9, (2015) Plant polyphenols are of great interest for drug discovery and drug development since many of these compounds have health-promoting activities as treatments against various diseases, such as diabetes, cancer, or heart diseases. However, the limited availabili... |
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Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.
Bioorg. Med. Chem. Lett. 15 , 1949-53, (2005) 1'S-1'-Acetoxychavicol acetate from the rhizomes of Alpinia galanga inhibited nitric oxide (NO) production in lipopolysaccharide-activated mouse peritoneal macrophages with an IC(50) value of 2.3 microM. To clarify the structure-activity relationship of 1'S-1... |
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Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).
Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011) Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids and esters such as methyl fumarate also interact with the r... |
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Contribution of cinnamic acid analogues in rosmarinic acid to inhibition of snake venom induced hemorrhage.
Bioorg. Med. Chem. 19 , 2392-6, (2011) In our previous paper, we reported that rosmarinic acid (1) of Argusia argentea could neutralize snake venom induced hemorrhagic action. Rosmarinic acid (1) consists of two phenylpropanoids: caffeic acid (2) and 3-(3,4-dihydroxyphenyl)lactic acid (3). In this... |
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Temporal changes in allocation and partitioning of new carbon as (11)C elicited by simulated herbivory suggest that roots shape aboveground responses in Arabidopsis.
Plant Physiol. 161(2) , 692-704, (2013) Using the short-lived isotope (11)C (t(1/2) = 20.4 min) as (11)CO(2), we captured temporal changes in whole-plant carbon movement and partitioning of recently fixed carbon into primary and secondary metabolites in a time course (2, 6, and 24 h) following simu... |
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Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells.
Biol. Res. 47(1) , 54, (2015) Zanthoxylum heitzii is a spice used to prepare several dishes and to treat tumors, syphilis, malaria, cardiac palpitations, urogenital infections in the west region of Cameroon, but the antitumor mechanisms and chemical composition are not yet investigated. T... |
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Combined experimental and computational investigation of the absorption spectra of E- and Z-cinnamic acids in solution: The peculiarity of Z-cinnamics.
J. Photochem. Photobiol. B, Biol. 148 , 128-35, (2015) Cinnamic acids are present in all kinds of plant tissues and hence in herbs and derived medicines, cosmetics and foods. The interest in their role in plants and their therapeutic applications has grown exponentially. Because of their molecular structure they ... |
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Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.
Bioorg. Med. Chem. 18 , 2337-45, (2010) The methanolic extract from the whole plants of Anastatica hierochuntica, an Egyptian herbal medicine, was found to inhibit melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells. Among the constituents isolated, anastatin A, silybin A, isosil... |