Bergenin structure
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Common Name | Bergenin | ||
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CAS Number | 477-90-7 | Molecular Weight | 328.271 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | 658.9±55.0 °C at 760 mmHg | |
Molecular Formula | C14H16O9 | Melting Point | 237-240 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 250.7±25.0 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of BergeninBergenin, a polyphenol, is a potent antinarcotic agent with antioxidant action. IC50 value: < 2.5 μM (antiplasmodial) [3]Target:In vitro: The naloxone-precipitated withdrawal symptom (jumping frequency) was significantly ameliorated (50% of control group) by administration of bergenin (20 mg/kg) in morphine-treated mice. Furthermore, morphine-induced down-regulation of glutathione (GSH) contents was reversed by bergenin administration in the frontal cortex and liver [2].In vivo: Bergenin attenuated inflammatory cell infiltration and decreased the concentration of NO, TNF-α, IL-1β, and IL-6, which were increased in LPS-induced mouse mastitis [1]. |
Name | Bengenin |
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Synonym | More Synonyms |
Description | Bergenin, a polyphenol, is a potent antinarcotic agent with antioxidant action. IC50 value: < 2.5 μM (antiplasmodial) [3]Target:In vitro: The naloxone-precipitated withdrawal symptom (jumping frequency) was significantly ameliorated (50% of control group) by administration of bergenin (20 mg/kg) in morphine-treated mice. Furthermore, morphine-induced down-regulation of glutathione (GSH) contents was reversed by bergenin administration in the frontal cortex and liver [2].In vivo: Bergenin attenuated inflammatory cell infiltration and decreased the concentration of NO, TNF-α, IL-1β, and IL-6, which were increased in LPS-induced mouse mastitis [1]. |
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Related Catalog | |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 658.9±55.0 °C at 760 mmHg |
Melting Point | 237-240 °C(lit.) |
Molecular Formula | C14H16O9 |
Molecular Weight | 328.271 |
Flash Point | 250.7±25.0 °C |
Exact Mass | 328.079437 |
PSA | 145.91000 |
LogP | 0.05 |
Vapour Pressure | 0.0±2.1 mmHg at 25°C |
Index of Refraction | 1.655 |
Storage condition | ?20°C |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | UQ0337200 |
Precursor 9 | |
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DownStream 3 | |
Studies on the chemical constituents and anticancer activity of Saxifraga stolonifera (L) Meeb.
Bioorg. Med. Chem. 16 , 1337-44, (2008) Saxifraga stolonifera, an evergreen dicotyledon, has been identified as an important resource in Chinese medicine due to its anticancer activity. In the present report, chemical components of S. stolo... |
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Simultaneous quantification of biomarkers bergenin and menisdaurin in the methanol extract of aerial parts of Flueggea virosa by validated HPTLC densitometric method.
J. Chromatogr. Sci. 53 , 824-9, (2015) A simple, sensitive high-performance thin-layer chromatography (HPTLC) method was developed for the simultaneous quantification of biomarker bergenin and menisdaurin in the methanol extracts of aerial... |
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A novel lactone from Tripterospermum chinense.
Yao Xue Xue Bao 47(11) , 1517-20, (2012) A novel lactone, tripterospermumcins E (1), along with four known compounds, sweroside (2), loganic acid (3), 8-epi-kingiside (4) and bergenin (5), were isolated from the aerial parts of Tripterosperm... |
Vakerin |
Ai Cha Su |
Bergenitol |
Bergenit |
Peltophorin |
CORYLOPSIN |
(+)-Bergenin |
3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2H)-one |
4-Methoxy-2-[tetrahydro-3,4,5-trihydroxy-6-(hydroxymethyl)pyran-2-yl]-a-resorcylic Acid d-Lactone |
Pyrano[3,2-c][2]benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy- |
3,4,4a,10b-Tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxypyrano[3,2-c][2]benzopyran-6(2H)-one |
BERGENIN |
Bergenin:Pyrano[3,2-c][2]benzopyran-6(2H)-one,3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-, [2R-(2,3,4,4a, 10b)]-, |
CUSCUTIN |
Ardisic Acid B |
MFCD00133120 |