Usnic acid

Usnic acid Structure
Usnic acid structure
Common Name Usnic acid
CAS Number 7562-61-0 Molecular Weight 344.315
Density 1.5±0.1 g/cm3 Boiling Point 638.2±55.0 °C at 760 mmHg
Molecular Formula C18H16O7 Melting Point 201-203 °C(lit.)
MSDS USA Flash Point 236.0±25.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Proton-shuttling lichen compound usnic acid affects mitochondrial and lysosomal function in cancer cells.

PLoS ONE 7 , e51296, (2012)

The lichen compound usnic acid (UA) is a lipophilic weak acid that acts as a proton shuttle and causes loss of mitochondrial inner membrane potential. In the current study we show that UA treatment induced the formation of autophagosomes in human cancer cells...