2-Methylindole

2-Methylindole Structure
2-Methylindole structure
Common Name 2-Methylindole
CAS Number 95-20-5 Molecular Weight 131.17
Density 1.1±0.1 g/cm3 Boiling Point 272.0±0.0 °C at 760 mmHg
Molecular Formula C9H9N Melting Point 57-59 °C(lit.)
MSDS Chinese USA Flash Point 112.5±11.3 °C
Symbol GHS05
GHS05
Signal Word Danger

Development of a quantitative method for the simultaneous analysis of the boar taint compounds androstenone, skatole and indole in porcine serum and plasma by means of ultra-high performance liquid chromatography coupled to high resolution mass spectrometry.

Food Chem. 187 , 120-9, (2015)

Boar taint is an off-odour occurring while heating meat or fat from boars. A method detecting the three compounds (androstenone, skatole and indole) simultaneously in blood would offer substantial advantages since it would allow monitoring the impact of reari...

The effect of skatole and androstenone on consumer response towards streaky bacon and pork belly roll.

Meat Science 110 , 52-61, (2015)

Consumer liking was assessed for streaky bacon and pork belly roll from entire male pigs with an androstenone (AND) content of up to 9.4 ppm and a skatole (SKA) content of up to 0.92 ppm in the back fat and castrates. No clear effect of either AND or SKA was ...

Degradation of substituted indoles by an indole-degrading methanogenic consortium.

Appl. Environ. Microbiol. 57(9) , 2622-7, (1991)

Degradation of indole by an indole-degrading methanogenic consortium enriched from sewage sludge proceeded through a two-step hydroxylation pathway yielding oxindole and isatin. The ability of this consortium to hydroxylate and subsequently degrade substitute...

Characterization of microbial dysbiosis and metabolomic changes in dogs with acute diarrhea.

PLoS ONE 10 , e0127259, (2015)

Limited information is available regarding the metabolic consequences of intestinal dysbiosis in dogs with acute onset of diarrhea. The aim of this study was to evaluate the fecal microbiome, fecal concentrations of short-chain fatty acids (SCFAs), as well as...

Synthesis and investigation of antimicrobial activity and spectrophotometric and dyeing properties of some novel azo disperse dyes based on naphthalimides.

Biotechnol. Prog. , doi:10.1002/btpr.2107, (2015)

A series of novel disperse dyes containing azo group were synthesized through a diazotization and coupling process. The 4-amino-N-2-aminomethylpyridine-1,8-naphthalimide was diazotized by nitrosylsulphuric acid and coupled with various aromatic amines such as...

Synthetic studies on indolocarbazoles: total synthesis of staurosporine aglycon.

Org. Lett. 13(6) , 1418-21, (2011)

A synthesis of staurosporine aglycon and its analogs was achieved in a 28-36% overall yield starting from 2-methylindole. The prominent key steps for the synthesis of the indolocarbazole alkaloids involved electrocyclization and nitrene insertion reactions.

Rh(III)-catalyzed tandem C-H allylation and oxidative cyclization of anilides: a new entry to indoles.

Org. Lett. 15(17) , 4576-9, (2013)

Rh(III)-catalyzed tandem C-H allylation and oxidative cyclization of anilides with allyl carbonates in the presence of a slight excess of AgSbF6 salt and Cu(OAc)2 as oxidant affords easy, economical access to important bioactive 2-methylindoles. The new react...

Free-radical damage to lipids, amino acids, carbohydrates and nucleic acids determined by thiobarbituric acid reactivity.

Int. J. Biochem. 14(7) , 649-53, (1982)

1. The thiobarbituric acid (TBA) reaction, widely applied to the detection of autoxidation in polyunsaturated fatty acids, can be used to measure free-radical damage to amino acids, carbohydrates and nucleic acids. 2. In all of these systems malondialdehyde (...

Real-time reaction monitoring using ion mobility-mass spectrometry.

Analyst 136(8) , 1728-32, (2011)

The potential of ion mobility (IM) spectrometry in combination with mass spectrometry (MS) for real-time reaction monitoring is reported. The combined IM-MS approach using electrospray ionization affords gas-phase analyte characterization based on both mass-t...

The oxidation of indole derivatives catalyzed by horseradish peroxidase is highly chemiluminescent.

Arch. Biochem. Biophys. 387(2) , 173-9, (2001)

The indole moeity is present in many substances of biological occurrence. Its metabolism, in most cases, involves an oxidative pathway. This study reports the oxidation of a series of indole derivatives, including several of biological origin, catalyzed by ho...