2,2'-DITHIODIETHANOL
2,2'-DITHIODIETHANOL structure
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Common Name | 2,2'-DITHIODIETHANOL | ||
|---|---|---|---|---|
| CAS Number | 1892-29-1 | Molecular Weight | 154.251 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 306.5±27.0 °C at 760 mmHg | |
| Molecular Formula | C4H10O2S2 | Melting Point | 25-27 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 149.3±22.4 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
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Introgression of leginsulin, a cysteine-rich protein, and high-protein trait from an Asian soybean plant introduction genotype into a North American experimental soybean line.
J. Agric. Food Chem. 63(11) , 2862-9, (2015) Soybean is an important protein source for both humans and animals. However, soybean proteins are relatively poor in the sulfur-containing amino acids, cysteine and methionine. Improving the content of endogenous proteins rich in sulfur-containing amino acids... |
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Increasing proteome coverage for gel-based human tear proteome maps: towards a more comprehensive profiling.
Biomed. Chromatogr. 29 , 1056-67, (2015) In situations where the molecular mechanism of many ocular disorders is unknown, owing to the difficulties associated with sampling from ocular tissues, human tear film can be a promising medium in ophthalmic research. The present study demonstrates an in-dep... |
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Reduction processes in fast atom bombardment mass spectrometry: interdependence of analyte and matrix redox potentials.
Biomed. Environ. Mass Spectrom. 19(10) , 628-34, (1990) The reduction of selected redox indicator dyes during fast atom bombardment mass spectrometry was investigated in several different matrices. Reduction is indicated by the incorporation of one or more hydrogens into the cation of the dye. The extent of reduct... |
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Purification and kinetic analysis of cytosolic and mitochondrial thioredoxin glutathione reductase extracted from Taenia solium cysticerci.
Exp. Parasitol. 149 , 65-73, (2015) Thioredoxin glutathione reductases (TGRs) (EC 1.8.1.9) were purified to homogeneity from the cytosolic (cTsTGR) and mitochondrial (mTsTGR) fractions of Taenia solium, the agent responsible for neurocysticercosis, one of the major central nervous system parasi... |
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Hydroxyethyl disulfide as an efficient metabolic assay for cell viability in vitro.
Toxicol. In Vitro 26(4) , 603-12, (2012) Cell viability assays have a variety of well known practical and technical limitations. All the available approaches have disadvantages, such as non-linearity, high background and cumbersome protocols. Several commonly used tetrazolium chemicals rely upon gen... |
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Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress.
J. Biol. Chem. 277(12) , 9929-35, (2002) Glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the oxidative pentose phosphate cycle, regulates the NADPH/NADP(+) ratio in eukaryotic cells. G6PD deficiency is one of the most common mutations in humans and is known to cause health prob... |
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Regulation of iodothyronine 5'-deiodinases: effects of thiol blockers and altered substrate levels in vivo and in vitro.
Endocrinology 126(5) , 2597-606, (1990) To study the physiological regulation of the iodothyronine 5'-deiodinases (I-5'D), we have examined the effects of some thiol blockers and of thyroid status on I-5'D activities both in vitro and in vivo. At low (less than 5 mM) concentrations of dithiothreito... |
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Reversible inactivation of horse liver aldehyde dehydrogenase by 2-hydroxyethyl disulfide.
Physiol. Chem. Phys. 12(6) , 483-95, (1980) Incubation of horse liver aldehyde dehydrogenase (aldehyde:NAD oxidoreductase, EC 1.2.1.3) with 2-hydroxyethyl disulfide formed mixed-disulfides between protein sulfhydryl groups and beta-mercaptoethanol. Reduction of aldehyde dehydrogenase activity may be as... |
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pO(2)-dependent NO production determines OPPC activity in macrophages.
Free Radic. Biol. Med. 48 , 189-95, (2010) Stimulated macrophages produce nitric oxide (NO) via inducible nitric oxide synthase (iNOS) using molecular O(2), L-arginine, and NADPH. Exposure of macrophages to hypoxia decreases NO production within seconds, suggesting substrate limitation as the mechanis... |
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Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein.
Biochemistry 45(7) , 2362-71, (2006) Redox-sensitive yellow fluorescent protein (rxYFP) contains a dithiol disulfide pair that is thermodynamically suitable for monitoring intracellular glutathione redox potential. Glutaredoxin 1 (Grx1p) from yeast is known to catalyze the redox equilibrium betw... |