Chlorprothixene hydrochloride
Chlorprothixene hydrochloride structure
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Common Name | Chlorprothixene hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 6469-93-8 | Molecular Weight | 352.32100 | |
| Density | N/A | Boiling Point | 461.8ºC at 760 mmHg | |
| Molecular Formula | C18H19Cl2NS | Melting Point | 221ºC | |
| MSDS | Chinese USA | Flash Point | 233.1ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Spatial receptive fields in the retina and dorsal lateral geniculate nucleus of mice lacking rods and cones.
J. Neurophysiol. 114 , 1321-30, (2015) In advanced retinal degeneration loss of rods and cones leaves melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) as the only source of visual information. ipRGCs drive non-image-forming responses (e.g., circadian photoentrainm... |
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Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay.
PLoS ONE 9(10) , e110800, (2014) Chloroquine was a cheap, extremely effective drug against Plasmodium falciparum until resistance arose. One approach to reversing resistance is the inhibition of chloroquine efflux from its site of action, the parasite digestive vacuole. Chloroquine accumulat... |
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Biologically active conformers of phenothiazines and thioxanthenes. Further evidence for a ligand model of dopamine D2 receptor antagonists.
J. Med. Chem. 36 , 2219-2227, (1993) Conformational analyses have been performed on several phenothiazine and thioxanthene dopamine antagonists using the MM2-87 program and parameter set. The compounds that were examined are thioridazine (2), methotrimeprazine (3), cis- and trans-chlorprothixene... |
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Effect of some psychotropic drugs on the activated macrophage-induced luminol-dependent chemiluminescence.
Pharmacol. Toxicol. 84 , 170-173, (1999) The effect of some psychotropic drugs on the activity of macrophages to produce superoxide radicals during phagocytosis was tested. Three-cyclic antidepressants, imipramine and amitriptyline, and the thioxanthene neuroleptic, chlorprothixene, were studied. Th... |
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Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same 'core' fraction of GABA(A) receptors.
Neurochem. Res. 23 , 1283-1290, (1998) Clozapine and several other antipsychotic/antidepressant drugs that fully or partially block GABA(A) receptors were tested at concentrations that reversed the inhibitory effect of 1 microM GABA on 35S-t-butylbicyclophosphorothionate ([35S]TBPS) binding to rat... |