1-Naphthalenol

1-Naphthalenol Structure
1-Naphthalenol structure
Common Name 1-Naphthalenol
CAS Number 90-15-3 Molecular Weight 144.170
Density 1.2±0.1 g/cm3 Boiling Point 288.0±0.0 °C at 760 mmHg
Molecular Formula C10H8O Melting Point 94-98ºC
MSDS Chinese USA Flash Point 144.0±10.6 °C
Symbol GHS05 GHS06 GHS09
GHS05, GHS06, GHS09
Signal Word Danger

Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.

Nat. Commun. 5 , 5215, (2014)

The hormone calcitonin (CT) is primarily known for its pharmacologic action as an inhibitor of bone resorption, yet CT-deficient mice display increased bone formation. These findings raised the question about the underlying cellular and molecular mechanism of...

Rosmarinic acid attenuates hepatic ischemia and reperfusion injury in rats.

Food Chem. Toxicol. 74 , 270-8, (2015)

Rosmarinic acid (RosmA) demonstrates antioxidant and anti-inflammatory properties. We investigated the effect of RosmA on liver ischemia/reperfusion injury. Rats were submitted to 60 min of ischemia plus saline or RosmA treatment (150 mg/kg BW intraperitoneal...

Local administration of stromal cell-derived factor-1 promotes stem cell recruitment and bone regeneration in a rat periodontal bone defect model.

Mater. Sci. Eng. C. Mater. Biol. Appl. 53 , 83-94, (2015)

Stromal cell-derived factor-1 (SDF-1) recruits adult stem/progenitor cells via its specific receptor, C-X-C motif receptor 4 (CXCR4), to promote heart, kidney and tendon regeneration, but little is known about the effects of SDF-1 on bone regeneration in peri...

Characterization of nitrogen-rich biomaterial-derived biochars and their sorption for aromatic compounds.

Environ. Pollut. 195 , 84-90, (2014)

Biochars from nitrogen-rich biomaterials (i.e., α-amylase, chitin and zein) were produced at different temperatures (i.e. 170, 250, 350 and 450 °C) and characterized, and their sorption for phenanthrene, naphthalene and 1-naphthol was investigated. The organi...

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

J. Med. Chem. 48 , 3269-79, (2005)

Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the...

Evaluation of the in vitro/in vivo potential of five berries (bilberry, blueberry, cranberry, elderberry, and raspberry ketones) commonly used as herbal supplements to inhibit uridine diphospho-glucuronosyltransferase.

Food Chem. Toxicol. 72 , 13-9, (2014)

In this study, we evaluated inhibitory potentials of popularly-consumed berries (bilberry, blueberry, cranberry, elderberry, and raspberry ketones) as herbal supplements on UGT1A1, UGT1A4, UGT1A6, UGT1A9, and UGT2B7 in vitro. We also investigated the potentia...

Evaluation of thein vitro/in vivodrug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition

Food Chem. Toxicol. 68 , 117-27, (2014)

• BST204 is a purified dry extract of ginseng containing high amounts of Rh2 and Rg3. • BST204 had only weak inhibitory effects on nine CYPs and five UGTs. • It is unlikely that BST204 alter pharmacokinetics of drugs metabolized by CYPs/UGTs.

Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro.

Antimicrob. Agents Chemother. 58(9) , 5036-46, (2014)

Macrolactin A (MA) and 7-O-succinyl macrolactin A (SMA), polyene macrolides containing a 24-membered lactone ring, show antibiotic effects superior to those of teicoplanin against vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureu...

Comparing immunocompetent and immunodeficient mice as animal models for bone tissue engineering.

Oral Dis. 21 , 583-92, (2015)

To understand the differences and similarities between immunocompetent and immunodeficient mice as ectopic transplantation animal models for bone tissue engineering.Osteogenic cells from mouse leg bones were cultured, seeded on β-TCP granules, and transplante...

3D cell culture and osteogenic differentiation of human bone marrow stromal cells plated onto jet-sprayed or electrospun micro-fiber scaffolds.

Biomed. Mater. 10 , 045019, (2015)

A major limitation of the 2D culture systems is that they fail to recapitulate the in vivo 3D cellular microenvironment whereby cell-cell and cell-extracellular matrix (ECM) interactions occur. In this paper, a biomaterial scaffold that mimics the structure o...