Loganin

Loganin Structure
Loganin structure
Common Name Loganin
CAS Number 18524-94-2 Molecular Weight 390.382
Density 1.5±0.1 g/cm3 Boiling Point 608.8±55.0 °C at 760 mmHg
Molecular Formula C17H26O10 Melting Point 222°C
MSDS Chinese USA Flash Point 217.9±25.0 °C

Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica.

Biol. Pharm. Bull. 34(8) , 1330-3, (2011)

Allergy-preventive activity of flower buds of Lonicera japonica THUNB. was found in the 35% EtOH extract (LJ) using an in vivo assay, The assay system uses monitoring of a decrease in blood flow (BF) in the tail vein of mice subjected to sensitization with he...

[Optimization of microwave-assisted extraction with RSM and HPLC determination for three iridoid glycosides in Cornus officinalis].

Zhong Yao Cai 34(7) , 1118-22, (2011)

To establish a method of microwave-assisted extraction and high performance liquid chromatographic (HPLC) for simultaneous determination of three iridoid glycosides including loganin, sweroside and cornuside in Cornus officinalis.

Anti-inflammatory and analgesic activities of SKLJI, a highly purified and injectable herbal extract of Lonicera japonica.

Biosci. Biotechnol. Biochem. 74(10) , 2022-8, (2010)

The parenteral route has many merits over the oral route, including greater predictability, reproducibility of absorption, and rapid drug action, but injectable phytomedicines are uncommon due to protein precipitating tannin and hemolytic saponin components. ...

Lamiridosins, hepatitis C virus entry inhibitors from Lamium album.

J. Nat. Prod. 72(12) , 2158-62, (2009)

Phytochemical study of the aqueous extract of the flowering tops of Lamium album led to identification of the antiviral iridoid isomers lamiridosins A and B (1, 2). These compounds were found to significantly inhibit hepatitis C virus entry (IC(50) 2.31 muM) ...

Overexpression of ORCA3 and G10H in Catharanthus roseus plants regulated alkaloid biosynthesis and metabolism revealed by NMR-metabolomics.

PLoS ONE 7 , e43038, (2012)

In order to improve the production of the anticancer dimeric indole alkaloids in Catharanthuse roseus, much research has been dedicated to culturing cell lines, hairy roots, and efforts to elucidate the regulation of the monoterpenoid indole alkaloid (MIA) bi...

The ORCA2 transcription factor plays a key role in regulation of the terpenoid indole alkaloid pathway.

BMC Plant Biol. 13 , 155, (2013)

The terpenoid indole alkaloid (TIA) pathway leads to the production of pharmaceutically important drugs, such as the anticancer compounds vinblastine and vincristine. Unfortunately, these drugs are produced in trace amounts, causing them to be very costly. To...

[Studies on the chemical constituents from stems and leaves of Lonicera macranthoides].

Zhong Yao Cai 34(2) , 218-20, (2011)

To research the chemical constituents from stems and leaves of Lonicera macranthoides.Various column chromatographies were employed to isolate and purify the constituents. Their structures were elucidated by spectral analysis (IR, MS, 1H-NMR, 13 C-NMR) and ch...

The pharmacological effects of morroniside and loganin isolated from Liuweidihuang Wan, on MC3T3-E1 cells.

Molecules 15(10) , 7403-14, (2010)

Liuweidihuang wan (LW), initially a well-known formula for curing "wu chi wu ruan", is commonly used nowadays for clinical treatment of postmenopausal osteoporosis (PO), but the identity of the effective substance(s) remains unclear. The present study was des...

Preparative purification of morroniside and loganin from Fructus corni by combination of macroporous absorption resin and HSCCC.

J. Chromatogr. Sci. 47(5) , 333-6, (2009)

A method for preparative purification of loganin and morroniside from Fructus corni was established by combination of macroporous absorption resin column separation and high-speed counter-current chromatography (HSCCC). The crude extracts obtained from Fructu...

Simultaneous determination of four marker components in Yukmijihwang Tang by high performance liquid chromatography/diode array detector.

Arch. Pharm. Res. 33(4) , 619-23, (2010)

Simultaneous determination method of four marker components, paeoniflorin, loganin, 5-hydroxymethyl-2-furaldehyde and paeonol in traditional herbal medicine, Yukmijihwang tang, was developed to achieve rapidly and systematic quality control by high performanc...