Levofloxacin hydrate
Levofloxacin hydrate structure
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Common Name | Levofloxacin hydrate | ||
|---|---|---|---|---|
| CAS Number | 138199-71-0 | Molecular Weight | 370.38 | |
| Density | 1.48g/cm3 | Boiling Point | 571.5ºC at 760mmHg | |
| Molecular Formula | C18H20FN3O4.0.5H2O | Melting Point | 214-216°C | |
| MSDS | N/A | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Evaluation of a dental pulp-derived cell sheet cultured on amniotic membrane substrate.
Biomed Mater Eng 25(2) , 203-12, (2015) Mesenchymal stem cells (MSC) are transplanted for periodontal tissue regeneration, and the periodontal ligament (PDL) is regenerated using a cultured cell sheet. This cultured cell sheet is prepared using PDL-derived cells, growth factors, and amniotic membra... |
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Poly(ADP-Ribose) Polymerase Inhibition Improves Corneal Epithelial Innervation and Wound Healing in Diabetic Rats.
Invest. Ophthalmol. Vis. Sci. 56(3) , 1948-55, (2015) We evaluated the effect of poly(ADP-ribose) polymerase (PARP) inhibition by using 1,5-isoquinolinediol (ISO) on corneal epithelial innervation in diabetic rats.ISO (3 mg/kg, intraperitoneal) or vehicle was administered to rats with diabetes induced by strepto... |
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Simple and accurate quantitative analysis of 20 anti-tuberculosis drugs in human plasma using liquid chromatography-electrospray ionization-tandem mass spectrometry.
J. Pharm. Biomed. Anal. 102 , 9-16, (2014) A simple and accurate liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method for the quantitation of 20 anti-tuberculosis (anti-TB) drugs in human plasma, was developed as a tool for therapeutic drug monitoring. Two protein precipitation methods w... |
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The effect of resveratrol on protecting corneal epithelial cells from cytotoxicity caused by moxifloxacin and benzalkonium chloride.
Invest. Ophthalmol. Vis. Sci. 56(3) , 1575-84, (2015) Moxifloxacin (MOX), a fourth generation fluoroquinolone (FQ), has a wide antibacterial spectrum, but may show cytotoxicity characterized by high productions of reactive oxygen species (ROS). This study investigated the protective role of a common antioxidant ... |
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Engineering hydrophobically modified chitosan for enhancing the dispersion of respirable microparticles of levofloxacin.
Eur. J. Pharm. Biopharm. 88(3) , 816-29, (2014) The potential of amphiphilic chitosan formed by grafting octanoyl chains on the chitosan backbone for pulmonary delivery of levofloxacin has been studied. The success of polymer synthesis was confirmed using FT-IR and NMR, whilst antimicrobial activity was as... |
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In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria.
Antimicrob. Agents Chemother. 59(1) , 467-74, (2014) AZD0914 is a new spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor with potent in vitro antibacterial activity against key Gram-positive (Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, and... |
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Helicobacter pylori antimicrobial resistance rates in the central region of Portugal.
Clin. Microbiol. Infect. 20(11) , 1127-33, (2014) Helicobacter pylori resistance to antimicrobial agents is steadily increasing. It is extremely important to be aware of the local prevalence of antibiotic resistance so as to adjust treatment strategies. During this single-centre, prospective study, we aimed ... |
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A real-time prospective evaluation of clinical pharmaco-economic impact of diagnostic label of 'penicillin allergy' in a UK teaching hospital.
J. Clin. Pathol. 67(12) , 1088-92, (2014) To perform a pharmaco-economic analysis of prescribing alternative antibiotics in patients with a diagnostic label of 'penicillin allergy' and assess whether collation of information from a structured history and liaison with the family physician could reduce... |
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Different antibiotic susceptibility between antrum and corpus of the stomach, a possible reason for treatment failure of Helicobacter pylori infection.
World J. Gastroenterol. 20(43) , 16245-51, (2014) To assess whether antibiotic resistance varies between the antrum and corpus of the stomach of patients that are either Helicobacter pylori (H. pylori) therapy-naive or pre-treated.H. pylori strains were isolated from antrum and corpus biopsies from 66 patien... |
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Clarithromycin-based standard triple therapy can still be effective for Helicobacter pylori eradication in some parts of the Korea.
J. Korean Med. Sci. 29(9) , 1240-6, (2014) We evaluated the antibiotic resistance rates and eradication rates of clarithromycin based triple therapy from 2005 to 2010 retrospectively. In addition, we investigated the mechanism of clarithromycin resistance in Helicobacter pylori strains isolated from K... |