Digoxigenin
Digoxigenin structure
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Common Name | Digoxigenin | ||
|---|---|---|---|---|
| CAS Number | 1672-46-4 | Molecular Weight | 390.51300 | |
| Density | 1.297 g/cm3 | Boiling Point | 589.4ºC at 760 mmHg | |
| Molecular Formula | C23H34O5 | Melting Point | 222 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 203ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A.
Biol. Open 4(2) , 146-54, (2015) The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors. On the route to their targets migrating cells and growing axons depend on both, directional information from neurotropic cues and ad... |
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Long-distance retinoid signaling in the zebra finch brain.
PLoS ONE 9(11) , e111722, (2014) All-trans retinoic acid (ATRA), the main active metabolite of vitamin A, is a powerful signaling molecule that regulates large-scale morphogenetic processes during vertebrate embryonic development, but is also involved post-natally in regulating neural plasti... |
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Local synthesis of interferon-alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells.
Arthritis. Res. Ther. 17 , 72, (2015) Type I interferons are pivotal in the activation of autoimmune response in systemic lupus erythematous. However, the pathogenic role of interferon-alpha in patients affected by lupus nephritis remains uncertain. The aim of our study was to investigate the pre... |
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Evidence for a role of the polysaccharide capsule transport proteins in pertussis pathogenesis.
PLoS ONE 9(12) , e115243, (2014) Polysaccharide (PS) capsules are important virulence determinants for many bacterial pathogens. Bordetella pertussis, the agent of whooping cough, produces a surface associated microcapsule but its role in pertussis pathogenesis remained unknown. Here we show... |
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Protective role of adenylate cyclase in the context of a live pertussis vaccine candidate.
Microbes Infect. 16(1) , 51-60, (2014) Despite high vaccination coverage, pertussis remains an important respiratory infectious disease and the least-controlled vaccine-preventable infectious disease in children. Natural infection with Bordetella pertussis is known to induce strong and long-lastin... |
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Efficient programmable gene silencing by Cascade.
Nucleic Acids Res. 43(1) , 237-46, (2015) Methods that permit controlled changes in the expression of genes are important tools for biological and medical research, and for biotechnological applications. Conventional methods are directed at individually changing each gene, its regulatory elements or ... |
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Early function of the Abutilon mosaic virus AC2 gene as a replication brake.
J. Virol. 89(7) , 3683-99, (2015) The C2/AC2 genes of monopartite/bipartite geminiviruses of the genera Begomovirus and Curtovirus encode important pathogenicity factors with multiple functions described so far. A novel function of Abutilon mosaic virus (AbMV) AC2 as a replication brake is de... |
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The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium.
Proc. Natl. Acad. Sci. U. S. A. 111(22) , E2251-60, (2014) Iron-sulfur clusters function as cofactors of a wide range of proteins, with diverse molecular roles in both prokaryotic and eukaryotic cells. Dedicated machineries assemble the clusters and deliver them to the final acceptor molecules in a tightly regulated ... |
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Functional significance of nuclear export and mRNA binding of meiotic regulator Spo5 in fission yeast.
BMC Microbiol. 14 , 188, (2014) Meiotic cells undergo two rounds of nuclear division and generate gametes. Previous studies have indicated that a number of transcription factors modulate the transcriptome in successive waves during meiosis and spore formation in fission yeast. However, the ... |
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The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase.
J. Immunol. 193(12) , 6161-71, (2014) The pathogenic bacterium Staphylococcus aureus actively evades many aspects of human innate immunity by expressing a series of small inhibitory proteins. A number of these proteins inhibit the complement system, which labels bacteria for phagocytosis and gene... |