4-Iodoaniline
4-Iodoaniline structure
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Common Name | 4-Iodoaniline | ||
|---|---|---|---|---|
| CAS Number | 540-37-4 | Molecular Weight | 219.023 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 268.7±23.0 °C at 760 mmHg | |
| Molecular Formula | C6H6IN | Melting Point | 61-63 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 116.3±22.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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cIEF for rapid pKa determination of small molecules: a proof of concept.
Eur. J. Pharm. Sci. 63 , 14-21, (2014) A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated cap... |
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Growth of Thin, Anisotropic, π-Conjugated Molecular Films by Stepwise "Click" Assembly of Molecular Building Blocks: Characterizing Reaction Yield, Surface Coverage, and Film Thickness versus Addition Step Number.
J. Am. Chem. Soc. 137 , 8819-28, (2015) We report the systematic characterization of anisotropic, π-conjugated oligophenyleneimine (OPI) films synthesized using stepwise imine condensation, or "click" chemistry. Film synthesis began with a self-assembled monolayer (SAM) of 4-formylthiophenol or 4-a... |
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Potential of neurotoxicity after a single oral dose of 4-bromo-, 4-chloro-, 4-fluoro- or 4-iodoaniline in rats.
J. Appl. Toxicol. 23(5) , 315-22, (2003) The potential for neurotoxicity after a single oral dose of four halogenated aniline derivatives--4-bromoaniline (4-BA), 4-chloroaniline (4-CA), 4- fluoroaniline (4-FA) and 4-iodoaniline (4-IA)--was given to rats was investigated at or near the lethal dosage ... |
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The effect of varying halogen substituent patterns on the cytochrome P450 catalysed dehalogenation of 4-halogenated anilines to 4-aminophenol metabolites.
Biochem. Pharmacol. 49(9) , 1235-48, (1995) The cytochrome P450 catalysed biotransformation of 4-halogenated anilines was studied in vitro with special emphasis on the dehalogenation to 4-aminophenol metabolites. The results demonstrated that a fluorine substituent at the C4 position was more easily el... |
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Selective hydrogenation of halogenated arenes using porous manganese oxide (OMS-2) and platinum supported OMS-2 catalysts.
Faraday Discuss. 188 , 451-66, (2016) Porous manganese oxide (OMS-2) and platinum supported on OMS-2 catalysts have been shown to facilitate the hydrogenation of the nitro group in chloronitrobenzene to give chloroaniline with no dehalogenation. Complete conversion was obtained within 2 h at 25 °... |
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In situ synthesis of thermochemically reduced graphene oxide conducting nanocomposites.
Nano Lett. 12(4) , 1789-93, (2012) Highly conductive reduced graphene oxide (GO) polymer nanocomposites are synthesized by a well-organized in situ thermochemical synthesis technique. The surface functionalization of GO was carried out with aryl diazonium salt including 4-iodoaniline to form p... |
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Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group.
Toxicology 117(1) , 1-11, (1997) The structural basis of dapsone (4,4'-diaminodiphenyl sulphone) haemotoxicity has been determined by investigation of the in vitro bioactivation of a series of 4-substituted arylamines. In the presence of rat liver microsomes, dapsone (100 microM) was the mos... |
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Differentiation of complex lipid isomers by radical-directed dissociation mass spectrometry.
Anal. Chem. 84(17) , 7525-32, (2012) Contemporary lipidomics protocols are dependent on conventional tandem mass spectrometry for lipid identification. This approach is extremely powerful for determining lipid class and identifying the number of carbons and the degree of unsaturation of any acyl... |
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Analyses of azopigments obtained from the delta fraction of bilirubin from mammalian plasma (mammalian biliprotein).
Biochem. J. 248(1) , 79-84, (1987) Azopigments were obtained from the delta fraction of bilirubin (mammalian biliprotein) in cholestatic sera of men, rats and guinea pigs by diazo reaction with diazotized p-iodoaniline and analysed by t.l.c. Delta bilirubin of men and rats generated both uncon... |
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Purification, characterization, and crystallization of an N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium.
Protein Expr. Purif. 12(3) , 371-80, (1998) The N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium has been expressed as a histidine-tagged fusion protein in Escherichia coli and purified to apparent homogeneity using single-step immobilized metal ion chromatography. Sufficient quantiti... |