glucosylmannitol
glucosylmannitol structure
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Common Name | glucosylmannitol | ||
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| CAS Number | 64519-82-0 | Molecular Weight | 344.312 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 788.5±60.0 °C at 760 mmHg | |
| Molecular Formula | C12H24O11 | Melting Point | 215-217°C | |
| MSDS | Chinese USA | Flash Point | 430.7±32.9 °C | |
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Assessment of isomalt for colon-specific delivery and its comparison with lactulose.
AAPS PharmSciTech 14(1) , 53-9, (2013) Lactulose is used as a triggering substance in a unique colon-specific delivery technology called CODESTM. Colonic microflora degrades lactulose and forms short-chain fatty acids to activate the CODESTM system. However, lactulose has been reported to cause a ... |
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Effect of isomalt consumption on faecal microflora and colonic metabolism in healthy volunteers.
Br. J. Nutr. 95(1) , 40-50, (2006) Due to its low digestibility in the small intestine, a major fraction of the polyol isomalt reaches the colon. However, little is known about effects on the intestinal microflora. During two 4-week periods in a double-blind, placebo-controlled, cross-over des... |
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Effects of isomalt consumption on gastrointestinal and metabolic parameters in healthy volunteers.
Br. J. Nutr. 94(4) , 575-81, (2005) The polyol isomalt (Palatinit) is a well established sugar replacer. The impact of regular isomalt consumption on metabolism and parameters of gut function in nineteen healthy volunteers was examined in a randomised, double-blind, cross-over trial with two 4-... |
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Dissolution profile of novel composite pellet cores based on different ratios of microcrystalline cellulose and isomalt.
J. Pharm. Sci. 101(8) , 2675-80, (2012) There is a growing interest towards the application of inert cores as starting materials for pharmaceutical pellet manufacturing. They serve as alternatives to develop and adapt a relatively simple manufacturing technology compared with an extrusion/spheronis... |
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Supramolecular elucidation of the quality attributes of microcrystalline cellulose and isomalt composite pellet cores.
J. Pharm. Biomed. Anal. 84 , 124-8, (2013) The major objective of this study was to disclose the relationships between the physical quality attributes and supramolecular structure of novel composite pellet cores containing microcrystalline cellulose (MCC) and isomalt in different ratios. The novel com... |
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What clients need to know about sugar replacers.
J. Am. Diet. Assoc. 100(4) , 466-9, (2000)
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Evaluation of drug release from coated pellets based on isomalt, sugar, and microcrystalline cellulose inert cores.
AAPS PharmSciTech 11(1) , 383-91, (2010) The objective of the present study was to investigate the effect of the pellet core materials isomalt, sugar, and microcrystalline cellulose on the in vitro drug release kinetics of coated sustained-release pellets as well as to evaluate the influence of diff... |
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The comparative gastrointestinal response of young children to the ingestion of 25 g sweets containing sucrose or isomalt.
Br. J. Nutr. 87(4) , 291-7, (2002) Sugar-free confectionery products containing the low-energy, non-cariogenic sweetener isomalt are widely available in the market place and increasingly aimed at children. However, over-consumption of such products may lead to gastrointestinal symptoms and/or ... |
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The comparative gastrointestinal responses of children and adults following consumption of sweets formulated with sucrose, isomalt and lycasin HBC.
Eur. J. Clin. Nutr. 56(8) , 755-64, (2002) To determine the gastrointestinal responses of children and adults following consumption of sucrose, isomalt and lycasin HBC and to compare these at two different dose levels in adults.Both studies were randomised, double-blind, cross-over designs.Fifty-one c... |
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Improved metabolic control after 12-week dietary intervention with low glycaemic isomalt in patients with type 2 diabetes mellitus.
Horm. Metab. Res. 41(12) , 886-92, (2009) The polyol isomalt (Palatinit) is a very low glycaemic sugar replacer. The effect of food supplemented with isomalt instead of higher glycaemic ingredients like sucrose and/or starch hydrolysates on metabolic control in patients with type 2 diabetes was exami... |