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64519-82-0

64519-82-0 structure
64519-82-0 structure
  • Name: glucosylmannitol
  • Chemical Name: Isomalt
  • CAS Number: 64519-82-0
  • Molecular Formula: C12H24O11
  • Molecular Weight: 344.312
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Lactate Dehydrogenase
  • Create Date: 2018-07-25 17:50:38
  • Modify Date: 2025-08-21 10:23:08
  • Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].

Name Isomalt
Synonyms 1-O-α-D-Glucopyranosyl-D-mannitol
Plaltinitol
PALATINOL
ISOMALT USP
MFCD00190708
PALATINIT
hydrogenated isomaltulose
glucosylmannitol
Isomaltitol
EINECS 203-252-1
D-mannitol, 1-O-a-D-glucopyranosyl-
1-O-a-D-glucopyranosyl-D-mannitol
D-Mannitol, 1-O-α-D-glucopyranosyl-
PALATINITOL
Description Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].
Related Catalog
In Vivo The chronic toxicity of orally administered isomalt as a part of diet has been studied in animals and it was found to be a safe substance. It did not affect the mortality rate of the animals, and there was no evidence of carcinogenicity, or adverse effects on fertility, reproductive performance or development[1].
References

[1]. Tuderman AK, et al. Isomalt and its diastereomer mixtures as stabilizing excipients with freeze-dried lactate dehydrogenase. Int J Pharm. 2018 Mar 1;538(1-2):287-295.

Density 1.7±0.1 g/cm3
Boiling Point 788.5±60.0 °C at 760 mmHg
Melting Point 215-217°C
Molecular Formula C12H24O11
Molecular Weight 344.312
Flash Point 430.7±32.9 °C
Exact Mass 344.131866
PSA 401.06000
LogP -5.72
Vapour Pressure 0.0±6.2 mmHg at 25°C
Index of Refraction 1.634
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ4394500
CHEMICAL NAME :
D-Glucitol, 6-O-alpha-D-glucopyranosyl-, mixed with 1-O-alpha-D-glucopyranosyl-D-mannitol
CAS REGISTRY NUMBER :
64519-82-0
LAST UPDATED :
199312
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H24-O11.C12-H24-O11
MOLECULAR WEIGHT :
688.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
125 mg/kg
SEX/DURATION :
female 5 day(s) pre-mating female 1-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 27,631,1989
Hazard Codes Xn
Risk Phrases R20/21/22
Safety Phrases 22-26-36/37/39-45
RIDADR NONH for all modes of transport
RTECS LZ4394500
HS Code 2940000000
HS Code 2940000000
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