glucosylmannitol

Modify Date: 2024-01-04 00:20:08

glucosylmannitol structure	Common Name	glucosylmannitol
	CAS Number	64519-82-0	Molecular Weight	344.312
	Density	1.7±0.1 g/cm3	Boiling Point	788.5±60.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₂₄O₁₁	Melting Point	215-217°C
	MSDS	Chinese USA	Flash Point	430.7±32.9 °C

Use of glucosylmannitol

Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].

Name	Isomalt
Synonym	More Synonyms

Description	Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase Research Areas >> Metabolic Disease
In Vivo	The chronic toxicity of orally administered isomalt as a part of diet has been studied in animals and it was found to be a safe substance. It did not affect the mortality rate of the animals, and there was no evidence of carcinogenicity, or adverse effects on fertility, reproductive performance or development[1].
References	[1]. Tuderman AK, et al. Isomalt and its diastereomer mixtures as stabilizing excipients with freeze-dried lactate dehydrogenase. Int J Pharm. 2018 Mar 1;538(1-2):287-295.

Density	1.7±0.1 g/cm3
Boiling Point	788.5±60.0 °C at 760 mmHg
Melting Point	215-217°C
Molecular Formula	C₁₂H₂₄O₁₁
Molecular Weight	344.312
Flash Point	430.7±32.9 °C
Exact Mass	344.131866
PSA	401.06000
LogP	-5.72
Vapour Pressure	0.0±6.2 mmHg at 25°C
Index of Refraction	1.634
Storage condition	2-8°C

glucosylmannitol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ4394500

CHEMICAL NAME :: D-Glucitol, 6-O-alpha-D-glucopyranosyl-, mixed with 1-O-alpha-D-glucopyranosyl-D-mannitol

CAS REGISTRY NUMBER :: 64519-82-0

LAST UPDATED :: 199312

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H24-O11.C12-H24-O11

MOLECULAR WEIGHT :: 688.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 125 mg/kg

SEX/DURATION :: female 5 day(s) pre-mating female 1-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 27,631,1989

Hazard Codes	Xn
Risk Phrases	R20/21/22
Safety Phrases	22-26-36/37/39-45
RIDADR	NONH for all modes of transport
RTECS	LZ4394500
HS Code	2940000000

HS Code	2940000000

Assessment of isomalt for colon-specific delivery and its comparison with lactulose.

AAPS PharmSciTech 14(1) , 53-9, (2013)

Lactulose is used as a triggering substance in a unique colon-specific delivery technology called CODESTM. Colonic microflora degrades lactulose and forms short-chain fatty acids to activate the CODES...

Effect of isomalt consumption on faecal microflora and colonic metabolism in healthy volunteers.

Br. J. Nutr. 95(1) , 40-50, (2006)

Due to its low digestibility in the small intestine, a major fraction of the polyol isomalt reaches the colon. However, little is known about effects on the intestinal microflora. During two 4-week pe...

Effects of isomalt consumption on gastrointestinal and metabolic parameters in healthy volunteers.

Br. J. Nutr. 94(4) , 575-81, (2005)

The polyol isomalt (Palatinit) is a well established sugar replacer. The impact of regular isomalt consumption on metabolism and parameters of gut function in nineteen healthy volunteers was examined ...

1-O-α-D-Glucopyranosyl-D-mannitol

Plaltinitol

PALATINOL

ISOMALT USP

MFCD00190708

PALATINIT

hydrogenated isomaltulose

glucosylmannitol

Isomaltitol

EINECS 203-252-1

D-mannitol, 1-O-a-D-glucopyranosyl-

1-O-a-D-glucopyranosyl-D-mannitol

D-Mannitol, 1-O-α-D-glucopyranosyl-

PALATINITOL

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: glucosylmannitol
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: glucosylmannitol
Price: ￥4766.0/10g ￥736.0/1g ￥296.0/250mg ￥2976.0/5g
Purity: 97.0%
Delivery: 2 Day
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Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Isomalt
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Isomalt
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Isomalt Crystals
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Taiwan Oyi peptide Co. Ltd
China
Product Name: Isomalt
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

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Price: ￥1650/10 mM * 1 mL in Water

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glucosylmannitol

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