Methyl methanesulfonate

Methyl methanesulfonate Structure
Methyl methanesulfonate structure
Common Name Methyl methanesulfonate
CAS Number 66-27-3 Molecular Weight 110.13
Density 1.2±0.1 g/cm3 Boiling Point 202.1±9.0 °C at 760 mmHg
Molecular Formula C2H6O3S Melting Point 20ºC
MSDS Chinese USA Flash Point 104.4±0.0 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Sodium fluoride promotes apoptosis by generation of reactive oxygen species in human lymphocytes.

J. Toxicol. Environ. Health A 77(21) , 1269-80, (2014)

Fluoride generated the attention of toxicologists due to its deleterious effects at high concentrations in human populations suffering from fluorosis and with in vivo experimental models. Interest in its undesirable effects has resurfaced due to the awareness...

In vitro toxicological assessment of iron oxide, aluminium oxide and copper nanoparticles in prokaryotic and eukaryotic cell types.

Drug Chem. Toxicol. 38 , 152-61, (2015)

Metallic nanoparticles (NPs) have a variety of applications in different industries including pharmaceutical industry where these NPs are used mainly for image analysis and drug delivery. The increasing interest in nanotechnology is largely associated with un...

Toxicological assessment and management options for boat pressure-washing wastewater.

Ecotoxicol. Environ. Saf. 114 , 164-70, (2015)

Boats are washed periodically for maintenance in order to remove biofoulants from hulls, which results in the generation of wastewater. This study aimed at evaluating the cyto/genotoxic and mutagenic properties of wastewater produced by pressure washing of bo...

Diet carotenoid lutein modulates the expression of genes related to oxygen transporters and decreases DNA damage and oxidative stress in mice.

Food Chem. Toxicol. 70 , 205-13, (2014)

Lutein (LT) is a carotenoid obtained by diet and despite its antioxidant activity had been biochemically reported, few studies are available concerning its influence on the expression of antioxidant genes. The expression of 84 genes implicated in antioxidant ...

Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both Allium anaphase-telophase and comet tests.

Cytotechnology 67(2) , 207-13, (2015)

Genotoxic effects of bromoform and chloroform, disinfection by-products of the chlorination of drinking water, were examined by using mitotic index (MI), mitotic phase, chromosome aberrations (CAs) and comet assay on root meristematic cells of Allium cepa. Di...

Genotoxicity of chlorpyrifos in freshwater fish Labeo rohita using Alkaline Single-cell Gel Electrophoresis (Comet) assay.

Drug Chem. Toxicol. 37(4) , 466-71, (2014)

Chlorpyrifos is a widely used insecticide of organophosphate group, which causes severe toxicological effects in non target aquatic organisms especially in fish. In the present study the genotoxic effects of sublethal concentrations of chlorpyrifos were obser...

Impact of nanosilver on various DNA lesions and HPRT gene mutations - effects of charge and surface coating.

Part. Fibre Toxicol. 12 , 25, (2015)

The main goal of this research was to study the interactions of a fully characterized set of silver nanomaterials (Ag ENMs) with cells in vitro, according to the standards of Good Laboratory Practices (GLP), to assure the quality of nanotoxicology research. W...

Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids.

Food Chem. Toxicol. 80 , 130-6, (2015)

Synthetic cannabinoids (SCs) cause similar effects as cannabis and are sold in herbal mixtures. Recent investigations indicate that some of these drugs possess genotoxic properties. Therefore, we tested representatives of two groups, namely, aminoalkylindoles...

Safety evaluation of the human-identical milk monosaccharide sialic acid (N-acetyl-d-neuraminic acid) in Sprague-Dawley rats.

Regul Toxicol Pharmacol 70(2) , 482-91, (2014)

N-Acetyl-d-neuraminic acid (Neu5Ac) is the predominant form of sialic acid (Sia) in humans, while other mammals express Sia as a mixture with N-glycolyl-d-neuraminic acid (Neu5Gc). Neu5Ac occurs in highest levels in the brain and in breast milk, and is theref...

Phytotoxicity and genotoxicity assessment of imazethapyr herbicide using a battery of bioassays.

Environ. Sci. Pollut. Res. Int. 22 , 19194-202, (2015)

The imazethapyr herbicide (formulation Verosil(®)) was evaluated for phytotoxicity and genotoxicity using a battery of bioassays: (1) the growth inhibition of the green alga Pseudokirchneriella subcapitata, (2) the root growth and germination of the higher pl...