2-Bromo-4-fluorobenzoic acid
2-Bromo-4-fluorobenzoic acid structure
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Common Name | 2-Bromo-4-fluorobenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 1006-41-3 | Molecular Weight | 219.008 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 294.3±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H4BrFO2 | Melting Point | 172-176 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 131.8±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Radiosynthesis and in vivo evaluation of 1-[18F]fluoroelacridar as a positron emission tomography tracer for P-glycoprotein and breast cancer resistance protein.
Bioorg. Med. Chem. 19(7) , 2190-8, (2011) Aim of this study was to label the potent dual P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor elacridar (1) with (18)F to provide a positron emission tomography (PET) radiotracer to visualize Pgp and BCRP. A series of new 1- and 2-... |
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Regioselective copper-catalyzed amination of bromobenzoic acids using aliphatic and aromatic amines.
J. Org. Chem. 71(8) , 3270-3, (2006) A chemo- and regioselective copper-catalyzed cross-coupling procedure for amination of 2-bromobenzoic acids is described. The method eliminates the need for acid protection and produces N-aryl and N-alkyl anthranilic acid derivatives in up to 99% yield. N-(1-... |
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Rapid synthesis and zebrafish evaluation of a phenanthridine-based small molecule library.
Org. Biomol. Chem. 9(7) , 2233-9, (2011) A Heck cyclisation approach is described for the rapid synthesis of a library of natural product-like small molecules, based on the phenanthridine core. The synthesis of a range of substituted benzylamine building blocks and their incorporation into the libra... |
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Neuroleptics with protracted action: 3-Fluoro derivatives of methiothepin and oxyprothepin and their 2-fluoro analogues. Kopicová Z, et al.
Collect. Czech. Chem. Commun. 40(11) , 3519-29, (1975)
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