OU749

OU749 Structure
OU749 structure
Common Name OU749
CAS Number 519170-13-9 Molecular Weight 361.44
Density 1.4±0.1 g/cm3 Boiling Point 565.6±52.0 °C at 760 mmHg
Molecular Formula C16H15N3O3S2 Melting Point N/A
MSDS Chinese USA Flash Point 295.9±30.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis.

Sci. Rep. 6 , 30033, (2016)

Although essential amino acids regulate mechanistic target of rapamycin complex 1 (mTORC1) and the integrated stress response (ISR), the role of cysteine is unknown. We found that in hepatoma HepG2 cells, cystine (oxidized form of cysteine) activated mTORC1 a...