2-(Dimethylamino)ethyl methacrylate
2-(Dimethylamino)ethyl methacrylate structure
|
Common Name | 2-(Dimethylamino)ethyl methacrylate | ||
|---|---|---|---|---|
| CAS Number | 2867-47-2 | Molecular Weight | 157.210 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 187.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C8H15NO2 | Melting Point | -50 °C | |
| MSDS | Chinese USA | Flash Point | 70.6±0.0 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
|
Controlled Endolysosomal Release of Agents by pH-responsive Polymer Blend Particles.
Pharm. Res. 32 , 2280-91, (2015) A key step of delivering extracellular agents to its intracellular target is to escape from endosomal/lysosomal compartments, while minimizing the release of digestive enzymes that may compromise cellular functions. In this study, we examined the intracellula... |
|
|
Fabrication of flexible, transparent and conductive films from single-walled carbon nanotubes with high aspect ratio using poly((furfuryl methacrylate)-co-(2-(dimethylamino)ethyl methacrylate)) as a new polymeric dispersant.
Nanoscale 7(15) , 6745-53, (2015) We synthesized poly((furfuryl methacrylate)-co-(2-(dimethylamino)ethyl methacrylate)) (p(FMA-co-DMAEMA)) for the dispersion of single-walled carbon nanotubes (SWCNTs) while maintaining their high aspect ratios. The nanotubes' length and height were 2.0 μm and... |
|
|
A facile strategy to functionalize gold nanorods with polycation brushes for biomedical applications.
Acta Biomater. 10(8) , 3786-94, (2014) The fabrication of highly efficient nonviral gene carriers with low cytotoxicity remains a challenge in gene therapy. This paper reports a facile strategy to combine the advantages of gold nanorods (Au NRs) and polycations through surface functionalization. D... |
|
|
Electrostatic Self-Assembly of Au Nanoparticles onto Thermosensitive Magnetic Core-Shell Microgels for Thermally Tunable and Magnetically Recyclable Catalysis.
Small 11 , 2807-16, (2015) A facile route to fabricate a nanocomposite of Fe3O4@poly[N-isopropylacrylamide (NIPAM)-co-2-(dimethylamino)ethyl methacrylate (DMAEMA)]@Au (Fe3O4@PND@Au) is developed for magnetically recyclable and thermally tunable catalysis. The negatively charged Au nano... |
|
|
Interfacial assembly of dendritic microcapsules with host-guest chemistry.
Nat. Commun. 5 , 5772, (2014) The self-assembly of nanoscale materials to form hierarchically ordered structures promises new opportunities in drug delivery, as well as magnetic materials and devices. Herein, we report a simple means to promote the self-assembly of two polymers with funct... |
|
|
In vitro study of the specific interaction between poly(2-dimethylamino ethylmethacrylate) based polymers with platelets and red blood cells.
Int. J. Pharm. 492 , 55-64, (2015) Poly(2-dimethylamino)ethyl methacrylate (PDMAEMA) is an attractive polycation frequently proposed as a non-viral vector for gene therapy. As expected for other cationic carriers, intravenous administration of PDMAEMA can result in its ionic complexation with ... |
|
|
Investigation of drug-polymer interaction in solid dispersions by vapour sorption methods.
Int. J. Pharm. 469(1) , 159-67, (2014) The objective of this study was to investigate the effect of different polymeric carriers in solid dispersions with an active pharmaceutical ingredient (API) on their water vapour sorption equilibria and the influence of the API-polymer interactions on the di... |
|
|
Smart thermo/pH responsive magnetic nanogels for the simultaneous delivery of doxorubicin and methotrexate.
Int. J. Pharm. 487 , 274-84, (2015) Two novel dual temperature/pH-sensitive superparamagnetic nanogels were developed with the aim of simultaneously delivering two different anticancer drugs, doxorubicin (DOX) and methotrexate (MTX). The studied copolymers were characterized by (1)H NMR, SEM, a... |
|
|
Programming the composition of polymer blend particles for controlled immunity towards individual protein antigens.
Vaccine 33 , 2719-26, (2015) In order for a more precise control over the quality and quantity of immune responses stimulated by synthetic particle-based vaccines, it is critical to control the colloidal stability of particles and the release of protein antigens in both extracellular spa... |
|
|
Polyelectrolyte complexes of poly[(2-dimethylamino) ethyl methacrylate]/chondroitin sulfate obtained at different pHs: I. Preparation, characterization, cytotoxicity and controlled release of chondroitin sulfate.
Int. J. Pharm. 477(1-2) , 197-207, (2014) For the first time, polyelectrolyte complex based on poly[(2-dimethylamino) ethyl methacrylate] (PDMAEMA) and chondroitin sulfate (CS) was prepared. The properties of novel material and precursors were investigated by WAXS, FTIR, TGA, SEM and DLS analysis. Th... |