Azulene
Azulene structure
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Common Name | Azulene | ||
|---|---|---|---|---|
| CAS Number | 275-51-4 | Molecular Weight | 128.171 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 220.7±7.0 °C at 760 mmHg | |
| Molecular Formula | C10H8 | Melting Point | 98-100 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 76.7±8.9 °C | |
| Symbol |
GHS09 |
Signal Word | ||
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Determination of descriptors for polycyclic aromatic hydrocarbons and related compounds by chromatographic methods and liquid-liquid partition in totally organic biphasic systems.
J. Chromatogr. A. 1361 , 240-54, (2014) Retention factors on several columns and at various temperatures using gas chromatography and from reversed-phase liquid chromatography on a SunFire C18 column with various mobile phase compositions containing acetonitrile, methanol and tetrahydrofuran as str... |
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Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors.
Bioorg. Med. Chem. Lett. 20(20) , 6129-32, (2010) A series of azulene-based derivatives were synthesized as potent inhibitors for receptor tyrosine kinases such as FMS-like tyrosine kinase 3 (FLT-3). Systematic side chain modification of prototype 1a was carried out through SAR studies. Analogue 22 was ident... |
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Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione.
J. Org. Chem. 76(16) , 6906-11, (2011) An efficient synthesis of the key building block for 17-epi-calctriol from the Hajos-Parrish dione involving a sequence of diastereoselective transformation of the azulene core and the side-chain construction is presented. |
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Efficiency of NaOCl and laser-assisted photosensitization on the reduction of Enterococcus faecalis in vitro.
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 102(4) , e93-8, (2006) To investigate the action of a red laser associated with a photosensitizer on the reduction of Enterococcus faecalis in dental root canal in vitro.Thirty prepared teeth with single canals were contaminated. The chemical group was irrigated with 0.5% NaOCl and... |
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Evaluation of topical external medicine for 5-fluorouracil-induced oral mucositis in hamsters.
Eur. J. Pharmacol. 551(1-3) , 152-5, (2006) Oral ulcerative mucositis is a common and painful toxicity associated with chemotherapy for cancer. Current treatment for chemotherapy-induced oral mucositis is largely palliative, and no adequate treatment with conclusive evidence exists. The purpose of this... |
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Self-assembly of porphyrin-azulene-porphyrin and porphyrin-azulene conjugates.
Org. Biomol. Chem. 7(12) , 2540-7, (2009) In this paper we report the synthesis and self-assembling behavior of new porphyrin-azulene-porphyrin and porphyrin-azulene conjugates. The porphyrin-azulene-porphyrin conjugate gelates a number of organic solvents, while the porphyrin-azulene conjugates form... |
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Novel azulene derivatives for the treatment of erectile dysfunction.
Bioorg. Med. Chem. Lett. 22(23) , 7151-4, (2012) Based on the dopamine D(4) receptor partial agonist FAUC 3019, a series of azulenylmethylpiperazines was synthesized and affinities for the monoaminergic GPCRs including dopamine, serotonin, histamine and α-adrenergic receptor subtypes were determined. Ligand... |
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Evaluation of cytochrome P450(BSbeta) reactivity against polycyclic aromatic hydrocarbons and drugs.
Biochem. Biophys. Res. Commun. 355(1) , 286-93, (2007) The oxidation of 10 polycyclic aromatic hydrocarbons (PAH) by cytochrome P450(BSbeta) using three different electron acceptors is reported. Three PAH were found to be substrates for the oxidation by P450(BSbeta), namely anthracene, 9-methyl-anthracene and azu... |
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Comprehensive assessment of the photomutagenicity, photogenotoxicity and photo(cyto)toxicity of azulene.
Mutat. Res. 723(2) , 129-33, (2011) The polycyclic aromatic hydrocarbon azulene and its naturally occurring derivative guaiazulene (1,4-dimethyl-7-isopropylazulene) are known to absorb light in the UV-vis region of the spectrum. Both compounds were reported to be mutagenic in the Salmonella typ... |
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A comprehensive investigation of the interrelationships between spectroscopy and photochemistry and substituents of some azulenic derivatives.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 69(1) , 272-7, (2008) Several azulenic dyes, including six azulene hydrocarbons, two azulene aldehydes, and two olefinic azulenes, have been synthesized to survey their photophysics and photochemistry. These azulenes display S(2)-->S(0) emission, but with several differences. This... |