Azulene structure
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Common Name | Azulene | ||
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CAS Number | 275-51-4 | Molecular Weight | 128.171 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 220.7±7.0 °C at 760 mmHg | |
Molecular Formula | C10H8 | Melting Point | 98-100 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 76.7±8.9 °C | |
Symbol |
GHS09 |
Signal Word |
Use of AzuleneAzulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity. Azulene, isolated from the distillation of chamomile oil, is a scaffold in medicinal chemistry[1][2][3]. |
Name | azulene |
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Synonym | More Synonyms |
Description | Azulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity. Azulene, isolated from the distillation of chamomile oil, is a scaffold in medicinal chemistry[1][2][3]. |
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Related Catalog | |
Target |
HIV |
In Vitro | Azulene is an interesting scaffold in medicinal chemistry as it resembles several other bicyclic aromatics that are frequently found in drugs. Azulene, a structural isomer of naphthalene, is a bicyclic nonbenzenoid aromatic hydrocarbon having a dipole moment due to the electron-rich five-membered ring and electron-deficient sevenmembered ring[1]. |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 220.7±7.0 °C at 760 mmHg |
Melting Point | 98-100 °C(lit.) |
Molecular Formula | C10H8 |
Molecular Weight | 128.171 |
Flash Point | 76.7±8.9 °C |
Exact Mass | 128.062607 |
LogP | 3.45 |
Vapour Pressure | 0.2±0.2 mmHg at 25°C |
Index of Refraction | 1.632 |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Precursor 9 | |
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DownStream 10 | |
HS Code | 2902909090 |
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Summary | 2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |
Determination of descriptors for polycyclic aromatic hydrocarbons and related compounds by chromatographic methods and liquid-liquid partition in totally organic biphasic systems.
J. Chromatogr. A. 1361 , 240-54, (2014) Retention factors on several columns and at various temperatures using gas chromatography and from reversed-phase liquid chromatography on a SunFire C18 column with various mobile phase compositions c... |
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Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors.
Bioorg. Med. Chem. Lett. 20(20) , 6129-32, (2010) A series of azulene-based derivatives were synthesized as potent inhibitors for receptor tyrosine kinases such as FMS-like tyrosine kinase 3 (FLT-3). Systematic side chain modification of prototype 1a... |
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Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione.
J. Org. Chem. 76(16) , 6906-11, (2011) An efficient synthesis of the key building block for 17-epi-calctriol from the Hajos-Parrish dione involving a sequence of diastereoselective transformation of the azulene core and the side-chain cons... |
Bicyclo[5.3.0]deca-2,4,6,8,10-pentaene |
EINECS 205-993-6 |
Cyclopentacycloheptene |
Azunol |
Bicyclo(5.3.0)-deca-2,4,6,8,10-pentaene |
MFCD00003810 |
Azulene |
Bicyclo(5.3.0)-1,3,5,7,9-decapentaene |
Bicyclo[5.3.0]decapentaene |
Bicyclo[0.3.5]deca-1,3,5,7,9-pentaene |
Azunamic |