2-Phenoxyethanamine
2-Phenoxyethanamine structure
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Common Name | 2-Phenoxyethanamine | ||
|---|---|---|---|---|
| CAS Number | 156-43-4 | Molecular Weight | 137.179 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 230.3±23.0 °C at 760 mmHg | |
| Molecular Formula | C8H11NO | Melting Point | 2-5 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 97.9±15.9 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
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Biotransformation and nitroglycerin-induced effects on antioxidative defense system in rat erythrocytes and reticulocytes.
Gen. Physiol. Biophys. 33(4) , 393-401, (2014) The effects of nitroglycerin (glyceryl trinitrate - GTN) are mediated by liberated nitric oxide (NO) and formed reactive nitrogen species, which induces oxidative stress during biotransformation in red blood cells (RBCs). The aim of this study was to evaluate... |
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Magnetic beads as an extraction medium for simultaneous quantification of acetaminophen and structurally related compounds in human serum.
Drug Test. Anal. 7 , 457-66, (2015) This paper describes a sample preparation method that complements a previously published liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay for acetaminophen and eight structurally-related compounds in human serum (C. Bylda, R. Thiele, U. Kobold,... |
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Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia.
Biochem. Pharmacol. 84(9) , 1196-206, (2012) Phenacetin has been used as an analgesic antipyretic but has now been withdrawn from the market due to adverse effects such as methemoglobinemia and renal failure. It has been suggested that metabolic activation causes these adverse effects; yet, the precise ... |
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Screening of specific inhibitors for human carboxylesterases or arylacetamide deacetylase.
Drug Metab. Dispos. 42(7) , 1103-9, (2014) Esterases catalyze the hydrolysis of therapeutic drugs containing esters or amides in their structures. Human carboxylesterase (CES) and arylacetamide deacetylase (AADAC) are the major enzymes that catalyze the hydrolysis of drugs in the liver. Characterizati... |
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Reactions of a sulfonamide antimicrobial with model humic constituents: assessing pathways and stability of covalent bonding.
Environ. Sci. Technol. 46(4) , 2102-11, (2012) The mechanism of covalent bond formation of the model sulfonamide sulfathiazole (STZ) and the stronger nucleophile para-ethoxyaniline was studied in reactions with model humic acid constituents (quinones and other carbonyl compounds) in the absence and presen... |
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Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice.
J. Natl. Cancer Inst. 79(5) , 1151-8, (1987) The carcinogenicity of bucetin [(3-hydroxy-p-butyrophenetidide) CAS: 1083-57-4], an antipyretic analgesic drug, was examined in 300 (C57BL/6 X C3H)F1 mice. Groups of 50 mice of each sex were treated with 1.5 or 0.75% bucetin in their basal diet for 76 weeks a... |
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The Assessment of Liver Reserve Function by Spectrophotometry based on Determination of Phenacetin and Paracetamol.
Clin. Lab. 61 , 1927-34, (2016) To establish a technical system for assessing liver reserve function based on spectrophotometry by detection of phenacetin and paracetamol in blood samples.Taking detected contents of phenacetin and paracetamol by high performance liquid chromatography (HPLC)... |
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On the chemistry of the reaction between N-acetylcysteine and 4-[(4-ethoxyphenyl)imino]-2,5-cyclohexadien-1-one, a 4-ethoxyaniline metabolite formed during peroxidase reactions.
Chem. Res. Toxicol. 4(4) , 489-96, (1991) 4-Ethoxyaniline (p-phenetidine) is oxidized by peroxidases to form several products, one of which is 4-[(4-ethoxyphenyl)imino]-2,5-cyclohexadien-1-one (1). This compound reacts with N-acetylcysteine (NAC) in methanol-phosphate buffers, generating at least fou... |
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Co-oxidation of xenobiotics.
Biochem. Soc. Trans. 13(5) , 847-50, (1985)
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Use of high-performance liquid chromatography in the measurement of in vitro acetylation in man.
J. Chromatogr. A. 353 , 329-37, (1986) Liquid chromatographic methods were developed for the study of the in vitro acetylation of the sulphonamide drug sulphamethazine and a series of aniline derivatives. The sensitivity of the methods have allowed data on the activity of the N-acetyltransferase e... |