(R)-(-)-α-Methylhistamine dihydrochloride

(R)-(-)-α-Methylhistamine dihydrochloride Structure
(R)-(-)-α-Methylhistamine dihydrochloride structure
Common Name (R)-(-)-α-Methylhistamine dihydrochloride
CAS Number 75614-89-0 Molecular Weight 198.09400
Density N/A Boiling Point N/A
Molecular Formula C6H13Cl2N3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Highly potent and selective ligands for histamine H3-receptors.

Nature 327 , 117, (1987)

New drugs selective for histamine H3-receptors can be used to establish that these receptors are involved in the feedback control of histamine synthesis and release, and to demonstrate their distribution in the brain and peripheral tissues. These drugs provid...

Effects of the histamine H3-agonist (R)-alpha-methylhistamine and the antagonist thioperamide on histamine metabolism in the mouse and rat brain.

J. Neurochem. 52 , 1388, (1989)

To study the feedback control by histamine (HA) H3-receptors on the synthesis and release of HA at nerve endings in the brain, the effects of a potent and selective H3-agonist, (R)-alpha-methylhistamine, and an H3-antagonist, thioperamide, on the pargyline-in...

Structure-activity relations of histamine analogs. XX. Absolute configuration and histamine-like activity of enantiomeric α-methyl histamines. Gerhard, et al.

Arch. Pharm. Res. 313 , 709, (1980)