sevoflurane
sevoflurane structure
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Common Name | sevoflurane | ||
|---|---|---|---|---|
| CAS Number | 28523-86-6 | Molecular Weight | 200.055 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 49.5±35.0 °C at 760 mmHg | |
| Molecular Formula | C4H3F7O | Melting Point | 50-60ºC | |
| MSDS | Chinese USA | Flash Point | -11.4±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Propofol increases morbidity and mortality in a rat model of sepsis.
Crit. Care 19 , 45, (2015) Severe sepsis is associated with approximately 50% mortality and accounts for tremendous healthcare costs. Most patients require ventilatory support and propofol is commonly used to sedate mechanically ventilated patients. Volatile anesthetics have been shown... |
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Protective effect of curcumin against contrast induced nephropathy in rat kidney: what is happening to oxidative stress, inflammation, autophagy and apoptosis?
Eur. Rev. Med. Pharmacol. Sci. 18(4) , 461-70, (2014) Currently, the number of imaging and interventional procedures that use contrast agents (CAs) is gradually increasing. Oxidative stress plays a significant role in its pathophysiology. Curcumin (CC) is a natural substance with strong antioxidant efficacy.In t... |
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Generation of suppressive blood cells for control of allograft rejection.
Clin. Sci. 128(9) , 593-607, (2015) Our previous studies in rats showed that incubation of monocytic dendritic cells (DCs) with the chemotherapeutic drug mitomycin C (MMC) renders the cells immunosuppressive. Donor-derived MMC-DCs injected into the recipient prior to transplantation prolonged h... |
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Dietary pectin-derived acidic oligosaccharides improve the pulmonary bacterial clearance of Pseudomonas aeruginosa lung infection in mice by modulating intestinal microbiota and immunity.
J. Infect. Dis. 211(1) , 156-65, (2015) A predominantly T-helper type 2 (Th2) immune response is critical in the prognosis of pulmonary Pseudomonas aeruginosa infection. But the mucosal and systemic immune responses can be influenced by the intestinal microbiota.We assessed the effect of microbiota... |
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Determination of sevoflurane and isopropyl alcohol in exhaled breath by thermal desorption gas chromatography-mass spectrometry for exposure assessment of hospital staff.
J. Pharm. Biomed. Anal. 106 , 218-23, (2015) Volatile anaesthetics and disinfection chemicals pose ubiquitous inhalation and dermal exposure risks in hospital and clinic environments. This work demonstrates specific non-invasive breath biomonitoring methodology for assessing staff exposures to sevoflura... |
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In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia.
Psychopharmacol. Ser. 231(16) , 3151-67, (2014) Here, we present the pharmacological characterisation of Lu AF64280, a novel, selective, brain penetrant phosphodiesterase (PDE) 2A inhibitor, in in vitro/in vivo assays indicative of PDE2A inhibition, and in vivo models/assays relevant to cognitive processin... |
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Subnormothermic ex vivo liver perfusion reduces endothelial cell and bile duct injury after donation after cardiac death pig liver transplantation.
Liver Transpl. 20(11) , 1296-305, (2014) An ischemic-type biliary stricture (ITBS) is a common feature after liver transplantation using donation after cardiac death (DCD) grafts. We compared sequential subnormothermic ex vivo liver perfusion (SNEVLP; 33°C) with cold storage (CS) for the prevention ... |
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Effect of dexemeditomedine and propofol on the prevention of emergence agitation following sevoflurane anesthesia in Egyptian children.
J. Egypt. Soc. Parasitol. 44(3) , 687-94, (2014) This study evaluated the effect of dexemeditomedine and propofol on the prevention of emergence agitation following sevoflurane anesthesia in children. Sixty children, aged 4-6 years, ASA I, who were undergoing inguinal hernia repair were enrolled after writt... |
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Analysis of transthoracic echocardiographic data in major vascular surgery from a prospective randomised trial comparing sevoflurane and fentanyl with propofol and remifentanil anaesthesia.
Anaesthesia 69(6) , 558-72, (2014) The aim of this study was to define pre-operative echocardiographic data and explore if postoperative indices of cardiac function after open abdominal aortic surgery were affected by the anaesthetic regimen. We hypothesised that volatile anaesthesia would imp... |
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The effects of general anaesthesia on memory in children: a comparison between propofol and sevoflurane.
Anaesthesia 69(2) , 118-23, (2014) We studied the effects of general anaesthesia on memory 7 days and 3 months following elective hernia surgery. Sixty children aged between 7 and 13 years were randomly allocated to receive either propofol or sevoflurane. Memory was classified into immediate, ... |