Sweroside

Sweroside Structure
Sweroside structure
Common Name Sweroside
CAS Number 14215-86-2 Molecular Weight 358.341
Density 1.5±0.1 g/cm3 Boiling Point 630.3±55.0 °C at 760 mmHg
Molecular Formula C16H22O9 Melting Point 100 °C
MSDS Chinese USA Flash Point 231.8±25.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Antibacterial and antifungal screening of Centaurium pulchellum crude extracts and main secoiridoid compounds.

Nat. Prod. Commun. 5(10) , 1525-30, (2010)

The main principles of C. pulchellum (Sw.) Druce, secoiridoid glycosides, have been studied as potent bioactive compounds. Here we scored their content in extracts of ten populations of this species. Antibacterial and antifungal assays of the extracts and pur...

Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils.

Phytother Res. 26(2) , 168-73, (2012)

Gentiana straminea Maxim. has been used widely as a traditional Chinese medicine for the treatment of rheumarthritis, icterepatitis, constipation, pain and hypertension. Five secoiridoids, gentiopicroside (GTP), 6'-O-(2-hydroxy-3-O-β-D-glucopyranosyl-benzoyl)...

[Simultaneous determination of five constituents in eight Qingyedan species derived from Swertia plants by HPLC].

Zhongguo Zhong Yao Za Zhi 38(9) , 1394-400, (2013)

To develop an HPLC method for simultaneous determination of swertiamarin, gentiopicroside, sweroside, mangiferin, erythrocentaurin, and to detect these five constituents in eight Qingyedans derived from Swertia mileensis, S. cincta, S. patens, S. punicea, S. ...

Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats.

Food Chem. Toxicol. 52 , 83-90, (2013)

This study is an attempt to evaluate the hepatoprotective activity of Gentiana asclepiadea L. against carbon tetrachloride-induced liver injury in rats. Methanol extracts of aerial parts (GAA) and roots (GAR) of G. asclepiadea at doses of 100, 200, and 400mg/...

Fagraldehyde, a secoiridoid isolated from Fagraea fragrans.

J. Nat. Prod. 71(12) , 2038-40, (2008)

A secoiridoid aglycone with an atypical skeleton, named fagraldehyde (1), together with several known secoiridoids (gentiopicroside (2), sweroside (3), and swertiamarin (4)) were isolated from the bark and leaves of Fagraea fragrans collected in Cambodia. The...

Effects of Gentiana lutea ssp. symphyandra on the central nervous system in mice.

Phytother Res. 16(7) , 627-31, (2002)

A methanolic extact of Gentiana lutea ssp. symphyandra roots has been investigated for its possible effects on the central nervous system of mice. At doses of 250 and 500 mg/kg (i.p.), the methanol extract of Gentiana roots caused a significant increase in th...

Transformation of naturally-occurring 1,9-trans-9,5-cis sweroside to all trans sweroside during acetylation of sweroside aglycone.

Phytochemistry 57(1) , 51-6, (2001)

From the rootstock of Scabiosa columbria L. loganin and sweroside were isolated. Sweroside showed moderate antibacterial activity. Pure sweroside was converted to the sweroside aglycone 1-acetoxy derivative (DABCO/Ac2O) after hydrolysis of the glucose unit. X...

Simultaneous quantification of seven bioactive components in Caulis Lonicerae Japonicae by high performance liquid chromatography.

Biomed. Chromatogr. 21(6) , 649-54, (2007)

This study presents a new HPLC method for the simultaneous determination of seven major components, namely chlorogenic acid, caffeic acid, loganin, sweroside, secoxyloganin, rutin and luteolin 7-O-glucoside in Caulis Lonicerae Japonicae, a commonly used tradi...

Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica.

Biol. Pharm. Bull. 34(8) , 1330-3, (2011)

Allergy-preventive activity of flower buds of Lonicera japonica THUNB. was found in the 35% EtOH extract (LJ) using an in vivo assay, The assay system uses monitoring of a decrease in blood flow (BF) in the tail vein of mice subjected to sensitization with he...

Bisindole alkaloids and secoiridoids from Alstonia macrophylla Wall. ex G. Don.

Fitoterapia 82(6) , 798-804, (2011)

The ethanolic extract from stems of a Thai medicinal plant, Alstonia macrophylla Wall. ex G. Don (Apocynaceae) showed a significant inhibitory effect on acetylcholinesterase (AChE) determined by using Ellman assay. Four compounds i.e., a bisindole alkaloid, m...