PKA Inhibitor Fragment (6-22) amide

PKA Inhibitor Fragment (6-22) amide Structure
PKA Inhibitor Fragment (6-22) amide structure
Common Name PKA Inhibitor Fragment (6-22) amide
CAS Number 121932-06-7 Molecular Weight 1868.06000
Density N/A Boiling Point N/A
Molecular Formula C80H130N28O24 Melting Point N/A
MSDS Chinese USA Flash Point N/A

Protein kinase inhibitor-(6-22)-amide peptide analogs with standard and nonstandard amino acid substitutions for phenylalanine 10. Inhibition of cAMP-dependent protein kinase.

J. Biol. Chem. 264 , 14579, (1989)

The minimal structure in the heat-stable inhibitor protein of cAMP-dependent protein kinase required for a low nanomolar potency of inhibition is the peptide Thr6-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-+ ++Ile22-NH2 (PKI-(6-22)-amide). Wh...